| 王小辉 葛来安 蓝阳 吴媛.黄芪汤加减联合穴位贴敷对慢传输型便秘患者
胃肠激素的影响[J].实用中西医结合临床,2021,21(9):5-7 |
| 黄芪汤加减联合穴位贴敷对慢传输型便秘患者
胃肠激素的影响 |
| Effect of Modified Huangqi Decoction Combined with Acupoint Application on Gastrointestinal Hormones in Patients withSlow Transit Constipation |
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| DOI： |
| 中文关键词: 慢传输型便秘 黄芪汤 穴位贴敷 胃肠激素 |
| 英文关键词: Slow%transit%constipation %Huangqi%decoction %Acupoint%application %Gastrointestinal%hormone |
| 基金项目:江西省中医药管理局科技计划项目（编号：2018A144）；
国家自然科学基金项目（编号：82060840） |
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| 中文摘要: |
| 目的：观察黄芪汤加减联合穴位贴敷治疗慢传输型便秘患者的临床疗效及对患者胃肠激素的影响。 方法：将符合纳入
标准的 120 例患者随机分为两组，观察组 60 例，采用黄芪汤加减联合穴位贴敷治疗；对照组 60 例，采用口服乳果糖联合枸橼酸莫
沙必利分散片治疗。两组均治疗 4 周，比较两组临床疗效，治疗前后症状积分及血清胃动素、 P 物质、血管活性肠肽水平。结果：观察
组总有效率为 95.00% ，显著优于对照组的 81.67% （ P ＜0.05 ）；治疗后观察组症状积分低于对照组（ P ＜0.05 ）；治疗后两组血清胃动
素、 P 物质水平均较治疗前升高，且观察组高于对照组（ P ＜0.05 ）；治疗后两组血清血管活性肠肽水平较治疗前降低（ P ＜0.05 ），且
观察组显著低于对照组（ P ＜0.05 ）。结论：黄芪汤加减联合穴位贴敷治疗慢传输型便秘患者疗效显著，能改善各项临床症状，其作用
可能与调节胃肠激素水平有关。 |
| 英文摘要: |
| Objective:%To%observe%the%clinical%efficacy%of%modified%Huangqi%decoction%combined%with%acupoint%application%in%the%
treatment%of%patients%with%slow%transit%constipation%and%its%influence%on%gastrointestinal%hormones.%Methods:%120%Patients%who%met%the%
inclusion%criteria%were%randomly%divided%into%two%groups,%the%observation%group% (60%cases)%was%treated%with%Huangqi%decoction%combined%
with%acupoint%application;%the%control%group%(60%cases)%was%treated%with%oral%lactulose%combined%with%mosapride%citrate%dispersible%tablets.%
Both%groups%were%treated%for%4%weeks,%and%compared%the%clinical%efficacy,%symptom%scores,%serum%motilin,%substance%P%and%vasoactive%
intestinal%peptide%levels%between%the%two%groups%before%and%after%treatment.%Results:%The%total%effective%rate%of%the%observation%group%
(95.00%)%was%significantly%better%than%that%of%the%control%group% (81.67%),% P ＜0.05;%after%treatment,%the%symptom%score%of%the%observation%
group%was%lower%than%that%of%the%control%group% ( P ＜0.05);%after%treatment,%the%levels%of%serum%Motilin%and%Substance%P%in%the%two%groups%
were%higher%than%those%before%treatment,%and%the%observation%group%was%higher%than%that%in%the%control%group%( P ＜0.05);%after%treatment,%the%
serum%Vasoactive%Intestinal%Peptide%levels%of%the%two%groups%were%lower%than%that%before%treatment% ( P ＜0.05),%and%the%observation%group%
was%significantly%lower%than%that%of%the%control%group% ( P ＜0.05).%Conclusion:%Huangqi%decoction%combined%with%acupoint%application%has%
significant%effect%in%the%treatment%of%Slow%Transit%Constipation,%which%can%improve%the%clinical%symptoms,%and%its%effect%may%be%related%to%
the%regulation%of%gastrointestinal%hormone%levels.% |
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