| 冯静娟 向锋 程健 苟晔荔.聚乙二醇4000散剂加理气复胃口服液防治肛肠术后排便困难的疗效观察[J].实用中西医结合临床,2016,16(11):11-13,50 |
| 聚乙二醇4000散剂加理气复胃口服液防治肛肠术后排便困难的疗效观察 |
| Observation the Curative Effect of Macrogol 4000 Powder Plus Liqifuwei Oral Liquid in the Treatment of Difficult Defecation after Anorectal Surgery |
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| DOI： |
| 中文关键词: 排便困难 肛肠术后 聚乙二醇4000散剂 理气复胃口服液 |
| 英文关键词: Difficult Defecation After Anorectal Surgery Macrogol 4 000 Powder Liqifuwei Oral Liquid |
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| 中文摘要: |
| 目的：探讨聚乙二醇4000散剂加理气复胃口服液防治肛肠疾病术后排便困难的效果及不良反应。方法：选取2012年1月~2013年1月在我院进行了肛肠手术的住院患者210例，随机分为聚乙二醇组、理气复胃组和联合用药组，每组70例，分别进行治疗，疗程7 d，观察三组患者的起效时间、临床疗效及不良反应发生的情况。结果：服药后60 h内，聚乙二醇组、理气复胃组和联合用药组分别有81.43%、65.71%和92.86%的患者起效，联合用药组起效的病例数明显高于其余两组，P＜0.05，聚乙二醇组起效的病例数高于理气复胃组，P＜0.05；理气复胃组和联合用药组的胃肠胀气评分在各个时间段均明显低于聚乙二醇组，P＜0.05，理气复胃组与联合用药组的胃肠胀气评分相比较，差异无统计学意义，P＞0.05；1周后，聚乙二醇组、理气复胃组和联合用药组的总有效率分别为85.71%、70.00%和95.71%，联合用药组的总有效率明显优于其余两组，P＜0.05，聚乙二醇组的总有效率优于理气复胃组，P＜0.05；三组的总不良反应率相比较差异无统计学意义，P＞0.05。结论：聚乙二醇4000散剂加理气复胃口服液防治肛肠疾病术后排便困难的效果明显优于单用聚乙二醇4000散剂或单用理气复胃口服液，并且不良反应无增加，因此这是一种有效且安全的防治肛肠术后排便困难的方法。 |
| 英文摘要: |
| Objective: To explore the curative effect and safety of macrogol 4000 powder plus Liqifuwei oral liquid in the treatment of difficult defecation after anorectal surgery. Methods: From January 2012 to January 2013, 210 patients of anorectal surgery in our hospital were randomly divided macrogol 4000 powder group, Liqifuwei oral liquid group, and combination group, each group with 70 cases. Each group was treated respectively. The course was 7 days, and observed the effective time, therapeutic efficacy and adverse reaction in each group. Results: Within 60 h after taking medicines, there were 81.43%、65.72% and 92.86% of patients in the macrogol 4 000 powder group, Liqifuwei oral liquid group, and combination group received the curative effect respectively, the number of the cases received the curative effect in the combination group was obviously higher than that of the rest two groups, P＜0.05， and the number of the cases received the curative effect in the macrogol 4000 powder group was higher than that of the Liqifuwei oral liquid group, P＜0.05.The flatulence scores of the Liqifuwei oral liquid group and the combination group were significantly lower than that of the macrogol 4 000 powder group in each period, P＜0.05, and there was no statistically significant difference between the Liqifuwei oral liquid group and the combination group, P＞0.05. After a week, the total effective rate of macrogol 4000 powder group, Liqifuwei oral liquid group and combination group was 85.71%, 70.00% and 95.71% respectively, and the total effective rate of the combination group was obviously better than that of the other two groups, P＜0.05, the total effective rate of the macrogol 4000 powder group was better than the Liqifuwei oral liquid group, P＜0.05. The difference of the total rates of adverse reaction of these three groups had no statistical significance in comparison, P＞0.05. Conclusion: Macrogol 4000 powder plus Liqifuwei oral liquid is more effective than macrogol 4000 powder alone or Liqifuwei oral liquid alone in the treatment of difficult defecation after anorectal surgery. Besides, there is no significant increase in adverse reactions, so the macrogol 4000 powder plus Liqifuwei oral liquid is an effective and safe therapeutic method in the treatment of difficult defecation after anorectal surgery. |
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