| 陈翠 张松 高培阳.四物汤加味治疗急性心力衰竭52例临床疗效观察[J].实用中西医结合临床,2015,15(5):6-7，50 |
| 四物汤加味治疗急性心力衰竭52例临床疗效观察 |
| Observation Study of Effects of Flavored Siwu Decoction for Actue Heart Failure Patients |
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| DOI： |
| 中文关键词: 急性心力衰竭 四物汤加味方 临床疗效观察 |
| 英文关键词: Acute heart failure, Flavored Siwu decoction Clinical curative observation |
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| 中文摘要: |
| 目的：观察四物汤加味方治疗急性心力衰竭的临床疗效。方法：收集自2012年9月~2014年6月因急性心力衰竭入住我院的92例患者，单纯西医治疗组（40例）作为A组，在西医治疗基础上加用四物汤加味方组（52例）作为B组，观察治疗后脑钠肽（NT-proBNP）、肌钙蛋白T、心脏超声测值的变化，并比较随访28 d患者心力衰竭再发作次数及心功能改善情况。结果：B组有效率为76.9%，A组有效率为55.0%，两组有效率及治疗后血浆NT-proBNP、肌钙蛋白T值比较，差异有统计学意义（P＜0.05）；两组治疗前后超声测值左心室射血分数（LVEF）及左心室舒张末期内径（LVEDd）比较，差异无统计学意义（P＞0.05）；两组患者治疗后28 d心力衰竭再发作次数比较，B组少于A组，差异有统计学意义（P＜0.05）。结论：四物汤加味方能够降低急性心力衰竭患者血清学测值（脑钠肽、肌钙蛋白T），并且能够改善心衰患者心功能情况，减少心衰再发作次数。 |
| 英文摘要: |
| Objective: To observe the effects of flavored Siwu decoction for acute heart failure (AHF) patients. Methods: 92 AHF patients were collected in our hospital from September 2012 to June 2014. In group A (control group) western medicine was given to 40 cases, in group B (treatment group) western medicine combined with flavored Siwu decoction were given to 52 cases, after treatment, changes of brain natriuretic peptide (NT-proBNP), troponin T and cardiac ultrasound measurements (LVEF and LVEDd) were compared, recurrence frequency of heart failure attacks and cardiac function improvement were followed for 28 days. Results: After treatment, the total effective rate was 76.9% in group B, the rate was 55.0% in group A, and the difference of plasma NT-proBNP, troponin T value were statistically significant (P＜0.05); the change of LVEF (%) and LVEDd was no statistical significance (P＞0.05) between groups. For the frequency of heart failure attacks in 28 d, the group B was better than that of group A, the difference was statistically significant (P＜0.05). Conclusion: Flavored Siwu decoction can reduce serological test value in patients with acute heart failure (brain natriuretic peptide, troponin), and can improve cardiac function in patients with heart failure, reduce heart failure attack frequency. |
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