| 郭璇 颜丽花 李田田 王小娟 徐寅 谭华梁 彭丽丽 刘芸.中医护理对功能性消化不良肝郁脾虚证脑肠肽CCK、5-HP的影响[J].实用中西医结合临床,2015,15(1):82-84 |
| 中医护理对功能性消化不良肝郁脾虚证脑肠肽CCK、5-HP的影响 |
| The Influence of Traditional Chinese Medicine (TCM) Nursing on CCK of Braingut Peptides and 5-HT of Liver-stagnation and Spleen-deficiency Syndrome with Functional Dyspepsia |
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| DOI： |
| 中文关键词: 功能性消化不良 肝郁脾虚证 中医护理 CCK 5-HT |
| 英文关键词: Functional dyspepsia Liver-stagnation and spleen-deficiency syndrome Traditional chinese medicine nursing CCK 5-HT |
| 基金项目:湖南省科学技术厅科技计划项目（编号：2013FJ4053）;湖南省中医药管理局中医护理特色技术重点研究室建设项目（编号：2014003） |
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| 中文摘要: |
| 目的：探讨中医护理对功能性消化不良（Functional dyspepsia，FD）肝郁脾虚证患者脑肠肽CCK、5-HT含量的影响。方法：选择确诊为FD肝郁脾虚证的60例患者并随机分为两组，对照组（多潘立酮组）与治疗组（多潘立酮片+中医情志护理）各30例，均治疗23 d。采用放射免疫法测定两组患者治疗前后空腹血CCK、5-HT水平。结果：治疗组、对照组总有效率分别为93.33%、76.67%，两组比较差异无统计学意义；但治疗组显效率为70.00%，明显高于对照组的36.67%（P＜0.05）。与治疗前比较，治疗组与对照组中医证候积分差异均有统计学意义（P＜0.01）；治疗后两组比较，差异有统计学意义（P＜0.05）。两组治疗后血CCK、5-HT较治疗前均降低，且差异有统计学意义（P＜0.05）。结论：中医情志护理治疗功能性消化不良肝郁脾虚证可能通过降低血中CCK、5-HT的含量，从而改善临床症状。 |
| 英文摘要: |
| Objective: To study the influence of TCM nursing on CCK of braingut peptides and 5-HT of liver-stagnation and spleen-deficiency syndrome with functional dyspepsia. Methods: 60 Patients were selected according to the standard of functional dyspepsia of liver-stagnation and spleen-deficiency syndrome, were randomly assigned to control group (domperidone group, n=30) and treatment group (domperidone+TCM emotional nursing, n=30) for 23 days. The changes of clinical symptoms and signs were observed before and after therapy, and the changes of serum CCK、5-HT were detected. Results: Total effective rate in the treatment group and the control group was 93.33% and 76.67% respectively, there was no significant difference between the two groups; but the obvious effective rate was 70.00% in the treatment group, it was significantly higher than that of the control group (36.67%, P<0.05). The difference of TCM syndrome was statistically significant (P<0.01) pre and post treatment in two groups, and there was statistically significant (P<0.05) between two groups after treatment. After treatment CCK and 5-HT were decreased in two groups, the difference after treatment between two groups was statistically significant (P<0.05). Conclusion: TCM Emotional nursing in treating functional dyspepsia of liver-stagnation and spleen-deficiency syndrome may improve the clinical symptoms through reducing serum CCK and 5-HT. |
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