文章摘要
顾冬云.护肝片治疗抗精神病药所致肝损害疗效观察[J].实用中西医结合临床,2013,(2):11-12
护肝片治疗抗精神病药所致肝损害疗效观察
  
DOI:
中文关键词: 护肝片  抗精神病药  肝损害
英文关键词: Liver-protecting tablets  Antipsychotic  Hepatic lesion
基金项目:
作者单位
顾冬云 江苏省常熟市第三人民医院 
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中文摘要:
      目的:探讨护肝片与联苯双酯滴丸治疗抗精神病药所致肝损害的临床疗效及不良反应。方法:选取相应患者,随机分为两组,研究组35例 ,口服护肝片,对照组35例,口服联苯双酯滴丸,疗程8周。每4周检测肝功能。结果:研究组治疗后丙氨酸氨基转移酶(ALT)下降明显,8周后研究组复常率为88.6%,对照组的复常率为85.7%(P >0.05)。结论:护肝片是一种安全、有效的治疗抗精神病药物所致肝损害的药物。
英文摘要:
      Objective:To study the difference in the effect of treating antipsychotic-induced hepatic lesion with Liver-protecting tablets or Bifendate pills.Methods:Patients were randomly divided into the study group and the control group.The study group 35 cases used Liver-protecting tablets and the control group 35 cases used Bifendate pills in eight weeks.To detection of liver function every 4 weeks.Results:The study group after treatment of alanine aminotransferase(ALT) decreased significantly.After 8 weeks, the recovery rate of the study group was 88.6%,and the control group was 85.7% (P >0.05).Conclusion:Liver-protecting tablets is a safe, effective treatment of antipsychotic-induced hepatic lesion.
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