| 陈利民 周逸.中西医结合治疗空洞性肺结核临床对照研究[J].实用中西医结合临床,2010,(3):5-6 |
| 中西医结合治疗空洞性肺结核临床对照研究 |
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| DOI： |
| 中文关键词: 空洞性肺结核 中西医结合疗法 百合固金汤 临床对照研究 |
| 英文关键词: Cavitary pulmonary tuberculosis Therapy of combining traditional Chinese and western medicine Baihegujin decoction Controlled clinical trial |
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| 中文摘要: |
| 目的：探讨中西医结合疗法治疗空洞性肺结核的临床疗效。方法：2007年10月~2009年2月期间，签署知情同意书后，根据患者意愿将就诊的空洞性肺结核患者分为治疗组（40例）和对照组（35例），两组均按标准化疗方案服用抗结核药物，治疗组加服加味百合固金汤，疗程6个月。主要观察治疗前后的胸部CT、痰涂片变化。结果：(1) 两组病例均未发生脱落现象。(2) 两组总有效率分别为97.5%（39/40）、68.6%（24/35），治疗组能显著提高临床疗效，?字2=13.058，P =0.001。 (3) 治疗组明显能促进空洞闭合，?字2=7.589，P =0.022。(4) 治疗组能显著促进结核病灶的吸收，?字2=7.254，P =0.027。(5)治疗组提高初治、复治病例痰涂片转阴率，但两组相比无统计学意义，P =1.000。结论：中西医结合疗法能显著提高空洞性肺结核临床疗效，促进空洞闭合及结核病灶的吸收。 |
| 英文摘要: |
| Objective:To investigate the therapeutic effect of treating Cavitary Pulmonary Tuberculosis with the therapy of combining traditional Chinese and western medicine.Methods:75 Patients with computerized tomography proven cavitary pulmonary tuberculosis were enrolled in this study from October,2007 to February, 2009 in Infectious Diseases Unit of People’s Hospital of Macheng City , Hubei Province. After giving written consensus, patients were divided into therapy group (n=40) or control group (n=35) by their intentions. Patients in both groups received standard therapeutic regimen of tuberculosis. Meanwhile, therapy group received traditional chinese medicine, modified Baihegujin Decoction. All patients were received 6 months treatment.Computerized tomography,acid fast stain test of sputum were examined before and after treatment,separately. Results:There were no patients of both group dropping out in 6 months period of treatment. The total effective rates in therapy group was 97.5%（39/40）, and in control group was 68.6%（24/35）,the difference between the two group was significant(?字2=13.058，P =0.001).The precipitate cavitary dininishedly the difference between the two group was significant(?字2=7.589，P =0.022),The resorption of focus of infection,the difference between the two group was significant(?字2=7.254，P =0.027).Conclusion:Therapy of combining traditional Chinese and western medicine in cavitary pulmonary tuberculosis could improve therapeutic effect, precipitate cavitary diminishedly and resorption of focus of infection.
Key words:Cavitary pulmonary tuberculosis;Therapy of combining traditional Chin |
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