| 周英惠 黄友佳 张吉.达英-35联合二甲双胍治疗多囊卵巢综合征临床观察[J].实用中西医结合临床,2009,(1):14-15 |
| 达英-35联合二甲双胍治疗多囊卵巢综合征临床观察 |
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| DOI： |
| 中文关键词: 达英-35 二甲双胍 多囊卵巢综合征(PCOS) |
| 英文关键词: Diane - 35 metformin polycystic ovary syndrome (PCOS) |
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| 中文摘要: |
| 目的：观察达英-35联合二甲双胍治疗多囊卵巢综合征(PCOS)的疗效。方法：选取2004年12月~2006年12月在我院门诊就诊的34例PCOS患者，测定治疗前后血清卵泡刺激素(FSH)、黄体生成素(LH)、睾酮(T)、空腹胰岛素（FINS）、腰／臀比值(WHR)、体重指数(BMI)以及她们的排卵、月经情况，然后进行比较。结果：治疗后腰／臀比值、体重指数、T及LH／FSH比值明显降低(P <0.05)。结论：达因- 35 与二甲双胍联合运用能有效改善肥胖型PCOS患者临床症状，恢复排卵及月经周期，降低胰岛素抵抗及高雄激素血症。 |
| 英文摘要: |
| Objective:To observe the efficacy of Diane - 35 combined with metformin treat polycystic ovary syndrome (PCOS).Methods:Thirty-four PCOS were enrolled in the study,The levels of luteinizing hormone（LH）and follicle stimulating hormone(FSH),testosterone(T),body mass index(BMI)，waist to hip ratio(WHR)，menstruation and the ovulation were measured both before and after the treatment.Results:After the treatment，the ratio of LH and FSH，T，BMI，WHR fast insulin were significantly decreased(P <0.05).Conclusion:The combined Diane-35 and metformin could effectively inhibit the synthetic of androgens of opatients.The PCOS patients treated with Diane - 35 combined with metformin might be effectively improve clinical symptom,recovery ovulation and menstrual onset. |
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