| 廖辉 汪受传 徐建亚 李华丽.金欣口服液含药血清对呼吸道合胞病毒黏附、膜融合影响的实验研究[J].实用中西医结合临床,2008,(1):3-4 |
| 金欣口服液含药血清对呼吸道合胞病毒黏附、膜融合影响的实验研究 |
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| DOI： |
| 中文关键词: 呼吸道合胞病毒 金欣口服液 含药血清 机制 黏附 侵入 |
| 英文关键词: Respiratory syncyntial virus Jin Xin Oral Liquid serum contained medicine mechanism adsorption penetration |
| 基金项目:江苏省普通高校研究生科研创新计划，国家自然科学基金（编号：30772822） |
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| 中文摘要: |
| 目的：研究金欣口服液含药血清对呼吸道合胞病毒（RSV）黏附、膜融合的影响。方法：在病毒和细胞接触期间采用转换温度方法观察金欣口服液含药血清对RSV黏附、侵入的影响。结果：温度转换前（黏附阶段）加入金欣口服液含药血清，实验组和对照组OD值无差异；温度转换后（侵入阶段）加入金欣口服液含药血清组OD值明显升高，与对照组比有显著性差异。结论：金欣口服液含药血清的抗病毒作用在呼吸道合胞病毒黏附后的膜融合及侵入阶段。 |
| 英文摘要: |
| Objective: To study the mechanism of antiviral activity of serum contained Jin Xin oral liquid inhibited respiratory syncyntial virus （RSV） infection of Hep-2 cells.Methods: By a temperature shift experiment，serum contained Jin Xin oral liquid was added during or after the period of contact between the RSV and cells，OD value were measured. Results: The OD value increased significantly when Jin Xin oral liquid was added after virus adsorption. Conclusion: The serum contained Jin Xin oral liquid inhibited the RSV penetration into the Hep-2 cells. |
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