宋昆 肖桂林 石燕.双黄连粉针剂抗乌头碱诱发大鼠心律失常的实验研究[J].实用中西医结合临床,2007,(6):88-89 |
双黄连粉针剂抗乌头碱诱发大鼠心律失常的实验研究 |
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DOI: |
中文关键词: 双黄连粉针剂 乌头碱 心律失常 |
英文关键词: Injection Shuanghuanglian Aconitine Arrhythmia |
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中文摘要: |
目的:观察双黄连粉针剂对抗乌头碱诱发大鼠实验性心律失常的作用。方法:静脉注射乌头碱复制大鼠心律失常动物模型,在预先静脉注射双黄连粉针剂60mg/kg、30mg/kg的基础上,观察其抗乌头碱诱发大鼠实验性心律失常的作用。结果:双黄连粉针剂可明显提高乌头碱致大鼠发生VP、VT、Vf的阈值。结论:双黄连粉针剂具有一定抗乌头碱致大鼠实验性心律失常的作用。 |
英文摘要: |
Objective:To observe the anti-arrhythmic effects of injection Shuanghuanglian on the experimental arrhythmic models produced by intravenously injecting aconitine.Methods:Reproduce the experimental arrhythmic models by intravenously injecting aconitine,injection Shuanghuanglian (60mg/kg、30mg/kg)were precautionary intravenously injected respectively,observed the anti-arrhythmic effects.Result:Injection Shuanghuanglian could significantly increase the dosages of aconitine inducing VP、VT、Vf in rats. Conclusion: Injection Shuanghuanglian exerteded anti-arrhythmic effects on the experimental arrhythmic models produced by intravenously injecting aconitine. |
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