| 彭苍骄 姚泽忠 管敏昌.肺表面活性物质治疗新生儿呼吸窘迫综合征的临床观察[J].实用中西医结合临床,2005,(4):9-10 |
| 肺表面活性物质治疗新生儿呼吸窘迫综合征的临床观察 |
|
| |
| DOI： |
| 中文关键词: 肺表面活性物质 固尔苏 新生儿呼吸窘迫综合征 呼吸机机械通气 临床观察 |
| 英文关键词: |
| 基金项目: |
|
| 摘要点击次数: 515 |
| 全文下载次数: 251 |
| 中文摘要: |
| 目的：探讨肺表面活性物质（PS）治疗新生儿呼吸窘迫综合征（NRDS）的疗效。方法：将30例NRDS的患儿早期给足量的固尔苏气管内使用,配以综合治疗措施,观察使用固尔苏前后肺功能指标、呼吸机参数、存活率、并发症发生率及肺泡充气程度。结果：使用后动脉氧分压（PaO2）、动脉二氧化碳分压（PaCO2）、动脉-肺泡氧分压比值（a/APO2）、氧合指数（OI）较用药前有明显的改善,差异有显著性（P <0.05）；呼吸机参数(除PEEP外）明显下降,差异有显著性意义（P <0. 05）。最后病死4例(13.33%)，出现肺炎11例(36.67%),肺出血5例（16.67%），颅内出血为2例(6.67%),肺气漏3例（10%）。同时，X线胸片显示肺野透亮度明显改善。结论：固尔苏能有效的改善NRDS肺的通气、换气功能和肺泡充气程度。 |
| 英文摘要: |
| Objective：To discuss the therapentic effection of pulmonary surfactant replacement in neonatal respiratory distress syndrome(NRDS).Methods：pneumono-furrtion Indictor Respirator Idex, Suruvor rate, Complication rate and alveoli aerification lever were observed in the 30 cases of NRDS treated with enoush curosurf in tradiea early and treated synthetically. Results ：Arterial O2 pressure (PaO2)，Arterial CO2 Pressure (PaCO2) Oxygenate Index(OI) were ameliated after theropy (P <0.05) and Respirator Index(except PEEP) was obviously lowered (P <0.05).In the end, 4 cases died(13.33%)， 11 case had pnewnina(36.67%)，5 cases had pneumovvhaseid(16.67%)，2 cases had inrtacranial hemorrhase (6.67%)， 3 cases had pnenmothorax(10%)and chest X-ray showed a significant improvement in the luns aerovation. Cohdusions： Curosurf can improve pulmonary oxygenation , ventilation and lung aerovation in NRDS infants. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
