| 黄琼 指导：徐伟建.参附注射液对压力后负荷性急性心衰大鼠血流动力学的影响[J].实用中西医结合临床,2005,(2):6-7 |
| 参附注射液对压力后负荷性急性心衰大鼠血流动力学的影响 |
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| DOI： |
| 中文关键词: 参附注射液 急性心力衰竭 血流动力学 实验研究 |
| 英文关键词: ShenFu parenteral solution acute congestive heart failure hemodynamics experiment investigation |
| 基金项目: |
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| 中文摘要: |
| 目的：研究参附注射液对急性心衰大鼠血流动力学的影响。方法：用腹主动脉缩窄造成急性心衰大鼠模型，观察参附注射液对急性心衰大鼠血流动力学各指标的影响。结果：参附注射液与西地兰、多巴酚丁胺比较，有同等的正性肌力作用（P>0.05），与模型组比较使LVSP、+dp/dtmax升高（P<0.01），但与西地兰组、多巴酚丁胺比较,参附注射液能同时降低LVEDP（P<0.01）。结论：参附注射液与西地兰、多巴酚丁胺同等的正性肌力作用，但它同时能降低左室舒张末内压，治疗舒张性心力衰竭。 |
| 英文摘要: |
| objective:to investigate the hemodynamics effect of ShenFu parenteral solution on acute congestive heart failure rat. Methods: to use coarctation of abdomial aorta to result in acute congestive heart failure rat. To observe the hemodynamics marker of acute congestive heart failure rat. Result:to compare ShenFu parenteral solution with cedilanid and dobutamine, they have tantamount positive action (P>0.05). To compare ShenFu pareteral solution bundle with model bundle, ShenFu parenteral solution can make LVSP、+dp/dtmax set-up (P<0.01), but to compare ShenFu parenteral solution with cedilanid and dobutamine , ShenFu parenteral solution can decrease LVEDP (P<0.01). Conclusion: to compare ShenFu parenteral solution with cedilanid and dobutamine. ShenFu parenteral solution have tantamount positive action , but it can decrease LVEDP and treat relax heart failure. |
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