文章摘要
黄琼 指导:徐伟建.参附注射液对压力后负荷性急性心衰大鼠血流动力学的影响[J].实用中西医结合临床,2005,(2):6-7
参附注射液对压力后负荷性急性心衰大鼠血流动力学的影响
  
DOI:
中文关键词: 参附注射液  急性心力衰竭  血流动力学  实验研究
英文关键词: ShenFu parenteral solution  acute congestive  heart failure hemodynamics  experiment investigation
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作者单位
黄琼 指导:徐伟建 湖北中医学院硕士研究生湖北省中医院 
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中文摘要:
      目的:研究参附注射液对急性心衰大鼠血流动力学的影响。方法:用腹主动脉缩窄造成急性心衰大鼠模型,观察参附注射液对急性心衰大鼠血流动力学各指标的影响。结果:参附注射液与西地兰、多巴酚丁胺比较,有同等的正性肌力作用(P>0.05),与模型组比较使LVSP、+dp/dtmax升高(P<0.01),但与西地兰组、多巴酚丁胺比较,参附注射液能同时降低LVEDP(P<0.01)。结论:参附注射液与西地兰、多巴酚丁胺同等的正性肌力作用,但它同时能降低左室舒张末内压,治疗舒张性心力衰竭。
英文摘要:
      objective:to investigate the hemodynamics effect of ShenFu parenteral solution on acute congestive heart failure rat. Methods: to use coarctation of abdomial aorta to result in acute congestive heart failure rat. To observe the hemodynamics marker of acute congestive heart failure rat. Result:to compare ShenFu parenteral solution with cedilanid and dobutamine, they have tantamount positive action (P>0.05). To compare ShenFu pareteral solution bundle with model bundle, ShenFu parenteral solution can make LVSP、+dp/dtmax set-up (P<0.01), but to compare ShenFu parenteral solution with cedilanid and dobutamine , ShenFu parenteral solution can decrease LVEDP (P<0.01). Conclusion: to compare ShenFu parenteral solution with cedilanid and dobutamine. ShenFu parenteral solution have tantamount positive action , but it can decrease LVEDP and treat relax heart failure.
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