| 樊璐,余薇,李莹.南昌地区血液筛查ELISA单试剂反应性献血者归队情况分析[J].实用中西医结合临床,2025,25(20): |
| 南昌地区血液筛查ELISA单试剂反应性献血者归队情况分析 |
| 南昌地区血液筛查ELISA单试剂反应性献血者归队情况分析 |
| 投稿时间：2025-08-31 修订日期：2025-09-22 |
| DOI： |
| 中文关键词: 献血者归队 归队检测 ELISA 单试剂反应性 南昌地区 |
| 英文关键词: blood donor reentry reentry testing ELISA single reagent reactivity Nanchang area |
| 基金项目:江西省卫生健康委员会科技计划项目（编号：202510625） |
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| 中文摘要: |
| 目的 分析南昌地区献血者归队情况，评估归队策略的科学性和有效性，评价本地区献血者归队工作质量及效能，为持续改进归队流程提供参考。方法 2015年—2024年使用ELISA和NAT方法对献血者归队血样进行三次归队检测，2025年调整检测策略，一次常规检测合格后开展CLIA、WB、TPPA方法补充试验。从血站管理信息系统采集2015年1月—2025年7月血液筛查HBV、HCV、HIV、TP感染标志物ELISA单项目且单试剂检测反应性、NAT无反应性的献血者归队信息，统计分析归队检测合格率、归队成功率、再次献血率、再次献血合格率、再次献血类型/次数/血量、再次献血检测不合格项目、再次献血合格献血者人口学特征、归队失败献血者检测不合格项目等数据。结果 2015年—2025年7月南昌地区140名主动申请归队且符合归队条件的献血者，归队检测合格率77.57%，归队成功率59.29%；2015年—2024年75名归队成功献血者，再次献血率78.67%，再次献血合格率91.53%，再次献血类型以捐献全血为主，献血次数≥3次占66.1%，献血总量259900mL，再次献血检测不合格5例；2015年—2024年54名归队成功再次献血合格献血者，男性占66.67%，30~49岁占72.23%，大学本科学历31.48%，职业“其他/个体业者”48.15%，本地户籍83.33%，既往捐献全血74.07%，既往献血次数≥5次59.26%，既往屏蔽项目占比TP＞HBsAg＞HCV＞HIV；2015年—2025年7月57名归队失败献血者，归队检测不合格占42.11%，未完成归队检测流程占57.89%。结论 南昌地区献血者归队策略合理有效，通过优化归队流程、完善检测方法，进一步提升献血服务水平，对维护献血者权益、减少血源流失、保障血液安全发挥重要作用。 |
| 英文摘要: |
| Objective To analyze the reentry status of blood donors in Nanchang area, evaluate the scientificity and effectiveness of the reentry strategy, assess the quality and efficiency of the local blood donor reentry work, and provide reference for continuous improvement of the reentry process. Methods From 2015 to 2024, ELISA and NAT methods were be used to conduct three tests on blood samples from reentrying blood donors. In 2025, the testing strategy is adjusted and supplementary tests using CLIA, WB, and TPPA methods are conducted after passing a routine test. Collect information on blood donors who underwent single item ELISA screening for HBV, HCV, HIV, and TP infection markers from January 2015 to July 2025 using the blood station management information system. Statistical analysis of data on the qualified rate, successful rate, redonation rate, qualified rate and type/frequency/volume of redonation, failed redonation test items, demographic characteristics of qualified redonation blood donors, and failed redonation blood donor test items. Results From 2015 to July 2025, 140 blood donors in the Nanchang area who voluntarily applied to reentry and met the conditions for reentrying to the team had a qualified rate of 77.57% and a success rate of 59.29%; From 2015 to 2024, 75 successful blood donors reentryed to the team, with a redonation rate of 78.67% and a redonation qualification rate of 91.53%. The main type of redonation was whole blood donation, with 66.1% donating blood ≥ 3 times. The total amount of blood donated was 259900mL, and 5 cases failed the redonation test; From 2015 to 2024, there were 54 qualified blood donors who have reentryed to the team and successfully donated blood again, including 66.67% male donors, 72.23% 30-49 year olds, 31.48% college graduates, 48.15% professional "others/self-employed", 83.33% local registered residence, 74.07% previous whole blood donors, 59.26% previous blood donors ≥ 5 times, and the proportion of existing shielding projects TP>HBsAg>HCV>HIV; From 2015 to July 2025, 57 blood donors who failed to reentry to the team, with 42.11% of them failing the reentry testing and 57.89% not completing the reentry testing process. Conclusion The reentry strategy for blood donors in the Nanchang area is reasonable and effective. By optimizing the reentry process and improving testing methods, the level of blood donation services can be further improved, which plays an important role in safeguarding the rights and interests of blood donors, reducing blood loss, and ensuring blood safety. |
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