文章摘要
围刺针法配合阿片类镇痛药对晚期肺癌患者中重度癌痛的治疗效果
Therapeutic effect of circumferential needling combined with opioid analgesics on moderate and severe cancer pain in advanced lung cancer patients
投稿时间:2024-11-22  修订日期:2024-12-06
DOI:
中文关键词: 肺癌  癌痛  镇痛药  针刺
英文关键词: lung cancer  Cancer  analgesics  acupuncture
基金项目:
作者单位邮编
杨大勇* 福建省罗源县中医院 350600
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中文摘要:
      目的:探析围刺针法同阿片类镇痛药向结合,用于治疗晚期肺癌中重度癌痛的临床价值。方法:以SPSS 24.0软件将62例于2023年4月~2024年4月在福建省罗源县中医院诊治的晚期肺癌中重度癌痛患者随机分为对照组、试验组,各31例。对照组予以阿片类镇痛药(盐酸羟考酮缓释片)治疗,试验组予以围刺针法配合阿片类镇痛药治疗,比较两组治疗后临床疗效,疼痛程度[视觉模拟评分法(VAS)、疼痛简明评估量表(BPI)],炎性因子[白介素-1(IL-1),白介素-6(IL-6),肿瘤坏死因子-α(TNF-α)]水平及生存质量[欧洲癌症研究和治疗组织肿瘤患者生存质量量表(EORTC QLQ C-30) 、肺癌患者生活质量测定量表(FACT-L)]。结果:治疗总有效率试验组为93.55%,与对照组的74.19%比较,明显更高(P<0.05);治疗后,VAS、BPI评分试验组与对照组比较,明显更低(P<0.05);治疗后,血清IL-1,IL-6,TNF-α水平试验组与对照组比较,明显更低(P<0.05);治疗后,EORTC QLQ C-30、FACT-L评分试验组与对照组比较,明显更高(P<0.05)。结论:围刺针法配合阿片类镇痛药可提高晚期肺癌中重度癌痛的治疗效果,达到确切镇痛作用,并能降低炎性因子水平,提高患者生存质量。
英文摘要:
      Objective: To explore the clinical value of circumferential needling combined with opioid analgesics in the treatment of moderate and severe cancer pain in advanced lung cancer. Methods: A total of 62 patients with moderate to severe cancer pain in advanced lung cancer diagnosed and treated in Luoyuan County Hospital of Traditional Chinese Medicine in Fujian Province from April 2023~April 2024 were randomly divided into control group and experimental group, with 31 cases in each group. The control group was treated with oxycodone hydrochloride extended-release tablets, and the experimental group was treated with circumferential needling method combined with opioid analgesics, and the clinical efficacy, pain level [visual analogue scale (VAS), pain concise assessment scale (BPI)], inflammatory factors [interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)] and quality of life [European Organization for Research and Treatment of Cancer Quality of Life Scale (EORTC) for Cancer Patients with Cancer] were compared QLQ C-30), Quality of Life Measurement Scale for Lung Cancer Patients (FACT-L)]. Results: The total effective rate of treatment was 93.55% in the experimental group, compared 74.19 in the control group (%), significantly higher(P<0.05), and the VAS and BPI scores in the experimental group were compared control group, significantly lower (P<0.05) after treatment, and the serum levels of IL-1, IL-6 and TNF-α in the experimental group were compared control group, significantly lower (P<0.05). It was significantly higher (P<0.05). Conclusion: Circumferential needling combined with opioid analgesics can improve the treatment effect of moderate to severe cancer pain in advanced lung cancer, achieve exact analgesic effect, reduce the level of inflammatory factors, and improve the quality of life of patients.
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