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| 清胰汤加减联合大黄芒硝贴外敷治疗急性胰腺炎的临床研究 |
| Clinical study on the treatment of acute pancreatitis by adding and subtracting Qing Pancreatic Tang combined with external application of rhubarb and mangosteen paste |
| 投稿时间：2024-09-13 修订日期：2024-10-16 |
| DOI： |
| 中文关键词: 急性胰腺炎 清胰汤 大黄芒硝贴 临床疗效 |
| 英文关键词: Acute Pancreatitis Qingyi decoction Rhubarb Glauber"s salt patch Clinical efficacy |
| 基金项目:广西壮族自治区中医药管理局自筹经费科研课题(NO.GXZYZ20210545) |
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| 中文摘要: |
| 目的：探究急性胰腺炎使用清胰汤加减联合大黄芒硝贴外敷方式进行治疗的临床效果，并研究该药方对患者体内指标影响程度，如血清淀粉酶、脂肪酶、炎症因子等。方法：选取我院消化内科2021年07月至2023年07月间收治的确诊为急性胰腺炎且年龄≥18岁的患者90例，随机分成对照组和实验组，每组45人。对照组使用西医常规疗法，实验组在此基础上应用清胰汤1号方进行灌肠（禁食期），同时采用大黄芒硝贴敷，开放饮食后采用胰汤2号口服治疗。比较两组治疗总有效率、住院天数、临床症状恢复时间，以及血清淀粉酶、脂肪酶、炎症因子水平变化。结果：两组治疗有效率均为100%，该指标无差异（P＞0.05）；两组患者的淀粉酶、脂肪酶都明显降低( P＜0.05) ，但实验组主要临床症状缓解时间明显短于对照组( P＜0.05) 。研究对象在治疗期间均没有发生治疗副作用。结论：传统西医治疗辅以中医疗法（清胰汤口服和灌肠、大黄芒硝外敷）能够降低胰酶水平，有效缩短急性胰腺炎患者临床症状缓解时间，其医治安全程度有所保证，治疗效果显著，可以广泛的应用到临床。 |
| 英文摘要: |
| To explore the clinical efficacy of treating acute pancreatitis with modified Qingyi Decoction combined with external application of rhubarb and mirabilite plaster, and to investigate the influence of this prescription on the patient's internal indicators, such as serum amylase, lipase, inflammatory factors, etc. Method: A total of 90 patients aged ≥18 years old diagnosed with acute pancreatitis admitted to the Department of Gastroenterology of our hospital from July 2021 to July 2023 were randomly divided into control group and experimental group, with 45 patients in each group. The control group was Objective：treated with conventional Western medicine therapy, and the experimental group was treated with enema (fasting period) based on Qingyitang Decoction No. 1, applied with glauberite of rhubarb, and was treated with Yitang No. 2 orally after an open diet. The total effective rate, hospitalization days, recovery time of clinical symptoms, and serum amylase, lipase and inflammatory factors were compared between the two groups. Result: The effective rate of the two groups was 100%, and there was no difference in this index(P>0.05)；The amylase and lipase in both groups were significantly reduced( P＜0.05),but the relief time of main clinical symptoms in the experimental group was significantly shorter than that in the control group( P＜0.05). No side effects occurred during treatment in either group.Conclusion: Traditional western medicine therapy combined with traditional Chinese medicine therapy can reduce the level of pancreatic enzyme and effectively shorten the time of clinical symptom relief in patients with acute pancreatitis. The treatment method is safe and has significant therapeutic effect, which can be widely used in clinical practice. |
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