| Objective: To explore the value of applying the synergistic treatment of paediatric lung-heat cough and asthma granules with cefozoxime injection in phlegm-heat-shut lung type of paediatric pneumonia and wheezing. Methods:From March 2022 to April 2024, 100 children with pneumonia and cough received by the Department of Integrative Chinese and Western Medicine of the hospital were selected and divided into the experimental group and the control group according to the simple random blind selection method, with 50 cases each. The control group was treated with cefazoxime injection on the basis of conventional symptomatic treatment, and the experimental group was treated with Ferekechuan granules on the basis of the control group. Before treatment, 7 days after treatment, 14 days after treatment, TCM symptom scores, serum inflammatory factors [interleukin-1β (IL-1β), procalcitonin (PCT), C-reactive protein (CRP)], lung function [tidal volume (TV), minute ventilation volume (VE), forced vital capacity (FVC), first second forced vital capacity (FEV1)] of the two groups were compared. Compare adverse reactions. Results: After 7 days of treatment and 14 days of treatment, the main symptom score, secondary symptom score and total score, IL-1β, PCT and CRP in two groups were lower than before treatment, and the experimental group was lower (P < 0.05). The levels of TV, VE, FVC and FEV1 in 2 groups were higher than before treatment, and those in experimental group were higher (P < 0.05). The incidence of adverse reactions in experimental group was 4.00%, which was lower than that in control group (16.00%) (P < 0.05). Conclusion: The application of lung-heat cough and asthma granules and cefozoxime injection in synergistic treatment of paediatric pneumonia with phlegm-heat closed lung type can reduce the level of serum inflammatory factors, improve the function of lungs and reduce the clinical signs of the children with a high degree of safety. |
