| To analyze the medication rules of traditional Chinese medicine in the treatment of semen liquefaction, and guide the clinical prescription. Methods: Search the clinical research literature on the treatment of non-liquefaction of semen by traditional Chinese medicine included in databases such as HowNet, Wanfang and Vip, select the prescription required for the study according to the inclusion criteria, enter it into the traditional Chinese medicine inheritance system, and conduct statistical analysis on the taste, meridian tropism, efficacy, frequency and correlation between drugs of traditional Chinese medicine. Results: A total of 151 prescriptions were included, involving 196 traditional Chinese medicines. The top five drugs used frequently were Salvia miltiorrhiza, Cortex Phellodendri, Radix Rehmanniae, Glycyrrhizae and Radix Paeoniae rubra. The efficacy of drugs is mainly heat-clearing and tonifying; The medicine tastes sweet and bitter; Cold and warm are the most important drugs; Meridians mainly focus on kidney, liver and spleen. "Phellodendron chinense - Anemarrhena asphodeloides" has the highest frequency of occurrence; The drug combination with the highest confidence is "Anemarrhena, Radix Rehmanniae Preparata → Cortex Phellodendri"; Cluster analysis obtained five core clusters. Conclusion: Traditional Chinese medicine is flexible in the treatment of non-liquefaction of semen, and generally follows the guiding principle of "invigorating the right and eliminating the evil, and restoring the function of gasification". It is mainly based on tonifying the kidney and removing turbidity, supplemented by heat clearing, spleen strengthening, blood circulation, and qi circulation, and attaches importance to the application of chemical medicine based on Zhibai Dihuang Pill, Yougui Pill, Cheng"s Bixie Fenqing Decoction, and Taohong Siwu Decoction. |
