| 刘艳艳.临床药师参与基层医院慢性阻塞性肺疾病急性加重期患者用药指导及监护效果分析[J].实用中西医结合临床,2024,24(13): |
| 临床药师参与基层医院慢性阻塞性肺疾病急性加重期患者用药指导及监护效果分析 |
| Clinical pharmacists involved in basic hospital acute exacerbation of chronic obstructive pulmonary disease patients medication guidance and monitoring effect analysis |
| 投稿时间：2024-04-07 修订日期：2024-06-13 |
| DOI： |
| 中文关键词: 慢性阻塞性肺疾病急性加重期 临床药师 基层医院 用药指导 |
| 英文关键词: acute exacerbation of chronic obstructive pulmonary disease clinical pharmacist Primary Hospital medication guidance |
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| 中文摘要: |
| 目的 探讨临床药师用药指导及监护干预下基层医院慢性阻塞性肺疾病急性加重期（Acute Exacerbation Of Chronic Obstructive Pulmonary Disease,AECOPD）患者在临床治疗效果。方法 选取2023年1月至2024年1月医院收治的第一诊断为AECOPD住院患者80例，按照随机数字表法分为常规组和干预组，各40例。常规组采取初始治疗方案在经管医生医嘱下治疗，干预组在常规组基础上临床药师全程参与教育及干预。治疗过程中设计用药依从性量表对两组患者的用药依从性进行评估，对治疗后两组患者肺功能、6 min步行距离、住院天数综合评定，考察临床药师参与基层医院AECOPD患者干预效果。结果 治疗前两组用药依从性评分相差不大，差异无统计学意义（P>0.05），治疗后干预组用药依从性优良率明显高于常规组（P＜0.05）；治疗后干预组FEV1、FVC均明显高于对常规组（P＜0.05），治疗后干预组6 min步行距离评分明显高于对照组（P＜0.05）；干预组改善症状时间、平均住院天数明显低于常规组（P＜0.05）。结论 临床药师参与基层医院AECOPD患者用药指导及监护，可显著提高其用药依从性，明显改善病情，缩短住院时间。 |
| 英文摘要: |
| Objective: To explore the clinical treatment effect of acute exacerbation of chronic obstructive pulmonary disease（AECOPD） patients in grassroots hospitals under the guidance and monitoring intervention of clinical pharmacists. Method: Eighty inpatients with the first diagnosis of AECOPD admitted to the internal medicine department of our hospital from January 2023 to January 2024 were selected. They were randomly divided into a control group and an intervention group in the order of admission using a random number table. Among them, 40 patients in the control group received initial treatment under the guidance of the management doctor, while 40 patients in the intervention group received full education and intervention from clinical pharmacists in addition to the control group. During the treatment process, a medication adherence scale was designed to evaluate the medication adherence of two groups of patients. After treatment, the lung function, 6-minute walking distance, and length of hospital stay of the two groups of patients were comprehensively evaluated, and the intervention effect of clinical pharmacists on AECOPD patients in grassroots hospitals was evaluated. Result: There was no significant difference in medication adherence scores between the two groups of patients before treatment (P>0.05), and the excellent rate of medication adherence in the intervention group was significantly higher than that in the conventional group after treatment (P<0.05); After treatment, the FEV1 and FVC in the intervention group were significantly higher than those in the control group (P<0.05), and the 6-minute walking distance score in the intervention group was significantly higher than that in the control group (P<0.05); The time for symptom improvement and average length of hospital stay in the intervention group were significantly lower than those in the control group (P<0.05). Conclusion: Clinical pharmacists participating in medication guidance and monitoring for AECOPD patients in grassroots hospitals can significantly improve their medication compliance, significantly improve their condition, and shorten hospital stay. |
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