| [Abstract] Objective To investigate the related factors and countermeasures of abnormal reaction of children receiving MMR vaccine in Zhangshu City from 2020 to 2022. Methods Children aged 8-24 months who received MMR vaccine in Zhangshu City from 2020 to 2022 were selected to collect data and record the abnormal reactions after MMR vaccine. The related influencing factors of the abnormal reactions after MMR vaccine were analyzed. Results There were 20 cases (8.22? ) of children with abnormal reaction after receiving MMR vaccine in Zhangshu City from 2020 to 2022. The incidence of local induration was the highest, followed by local pain, allergic rash, fever, vomiting, lymph node enlargement, paroxysm, diarrhea. Univariate analysis showed that the age of 8-12 months, the first time receiving MMR vaccine, the abnormal reaction after vaccination, and the rural area of residence were associated with the abnormal reaction after MMR vaccine, and the difference was statistically significant (P < 0.05). Gender and vaccination month were not associated with abnormal reactions after MMR vaccination, and there was no statistical significance (P > 0.05). Logistic regression analysis showed that the age of 8-12 months (β=1.582, OR=4.865, 95%CI=1.768-13.391), the first vaccination with MMR vaccine (β=1.621, OR=5.057, 95%CI=1.690-15.132), had an abnormal reaction after vaccination (β=8.968, OR=7851.148, 95%CI=4001.103-15405.883), lived in rural areas (β=1.082, OR=2.949, 95%CI=1.205-7.217) was the risk factor for abnormal reaction after MMR vaccination (P < 0.05). Conclusion The age, the number of MMR vaccination, the occurrence of abnormal reaction after vaccination and the place of residence of children affected the abnormal reaction after vaccination. |
