| 【Abstract】Objective To observe the effect of nourishing blood and removing cold prescription on wind-dampness-cold arthralgia and the influence of hemorheology indexes and TCM symptoms.Methods Research into the wind raw arthralgia patients (may, 2021 to November 2019) total 102 cases of group study, grouping method for the random number table method, average divided into control group and observation group, the 51 cases, control group patients with oral celecoxib treatment, observation group of patients with oral celecoxib combined with nourishing blood by cold treatment, at the same time data observation: Curative effect, changes of hemorheological indexes (RBC specific volume and RBC rigidity index, whole blood hypocut reduction viscosity), changes of TCM syndromes (joint pain and adverse flexion and extension, muscle pain and numbness, pain or swelling, weak mouth and no desire to drink, etc.), changes of pain scale (visual simulated pain score, VAS score, knee function (LKSS) score, quality of life (GQOLi-74) score, adverse reactions.Results The total effective rate was 96.08% (49/51) in the observation group and 84.31% (43/51) in the control group, which was higher in the observation group, P < 0.05; Before treatment, the comparison of TCM syndromes (joint pain and adverse flexion and extension, muscle numbness and pain or swelling, weak mouth and no desire to drink, etc.), hemorheological indexes (RBC specific volume and RBC rigidity index, whole blood hypocut reduction viscosity), VAS score, LKSS score and GQOLI-74 score in 2 groups, P > 0.05. After treatment, TCM syndromes (joint pain and adverse flexion and extension, muscle numbness and pain or swelling, weak mouth and no appetite to drink, etc.), hemorheology indexes (RBC specific volume and RBC rigidity index, whole blood hypocut reduction viscosity), VAS score, LKSS score, GQOLi-74 score and other indexes of patients in the two groups were better than the control group. After treatment, TCM syndromes (joint pain and adverse flexion and extension, muscle numbness and pain or swelling, weak mouth and no appetite to drink, etc.), hemorheology indexes (RBC specific volume and RBC rigidity index, whole blood reduced viscosity), VAS score, LKSS score and GQOLI-74 score in observation group were better than those in control group, P < 0.05; Observation group: 1 case nausea, 1 case drowsiness; Control group: 1 case nausea, 1 case headache; The incidence of adverse reactions was low in both groups (P > 0.05).Conclusion Nourishing blood and removing cold can significantly improve the clinical efficacy of patients with wind-dampness-cold arthralgia, with better recovery, fewer side reactions, safe and reliable. |
