| 章淼，易遵军，徐丰改.加味八珍汤治疗气血亏虚型肺癌癌因性疲乏效果研究[J].实用中西医结合临床,2023,23(2):6-9 |
| 加味八珍汤治疗气血亏虚型肺癌癌因性疲乏效果研究 |
| Effect Study of Modified Bazhen Decoction on Cancer-Related Fatigue of Lung Cancer with Deficiency of Qi and Blood |
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| DOI： |
| 中文关键词: 肺癌 气血亏虚 癌因性疲乏 加味八珍汤 |
| 英文关键词: Lung cancer Deficiency of Qi and Blood Cancer-related fatigue Modified Bazhen decoction |
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| 中文摘要: |
| 目的：探讨加味八珍汤治疗气血亏虚型肺癌癌因性疲乏的效果。方法：选取成都新都东立中医医院、兴文县中医医院及四川省中西医结合医院收治的64例气血亏虚型肺癌患者，按随机数字表法分为观察组和对照组，各32例。对照组给予西医常规治疗，观察组在对照组的基础上联合加味八珍汤治疗。比较两组患者治疗后卡氏（KPS）评分改善情况、治疗前后T淋巴细胞亚群及中医证候积分。结果：观察组治疗后KPS评分改善率高于对照组（P＜0.05）；观察组治疗后CD3+、CD4+、CD4+/CD8+均高于对照组，差异有统计学意义（P＜0.05）；观察组治疗后中医证候积分低于对照组（P＜0.05）。结论：加味八珍汤治疗联合常规治疗气血亏虚型肺癌癌因性疲乏患者，能有效提高生活质量及免疫功能，缓解临床症状。 |
| 英文摘要: |
| Objective: To explore the effect of modified Bazhen decoction on cancer-related fatigue of lung cancer with deficiency of Qi and Blood. Methods: Sixty-four patients with lung cancer of deficiency of Qi and Blood admitted to Chengdu Xindu Dongli hospital of traditional chinese medicine, Xingwen hospital of traditional chinese medicine and Sichuan integrated traditional and western medicine hospital included in observation group (n=32) and control group (n=32) by a random number table. The control group was treated with conventional western medicine for radiotherapy and chemotherapy, and the observation group was treated with modified Bazhen decoction on the basis of control group. The improvement of KPS scores, T lymphocyte subsets and TCM symptom scores before and after treatment were compared between the two groups. Results: The improvement rate of KPS scores was higher in the observation group than that of the control group (P＜0.05); after treatment, CD3+, CD4+ and CD4+/CD8+ in observation group were higher than those in the control group, and the differences were statistically significant (P＜0.05); TCM syndrome scores of the observation group was lower than that of the control group after treatment (P＜0.05). Conclusions: Modified Bazhen decoction combined with conventional treatment can effectively improve the quality of life and immune function of patients with cancer-related fatigue of lung cancer due to deficiency of Qi and Blood, and alleviate clinical symptoms. |
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