文章摘要
陈嘉琪,史秀丽,谢昌营,黄雪云,吴娜.黄芩汤治疗溃疡性结肠炎的临床试验类文献的概述[J].实用中西医结合临床,2023,23(1):91-95
黄芩汤治疗溃疡性结肠炎的临床试验类文献的概述
Literature Review of Clinical Trials on Huangqin Decoction in the Treatment of Ulcerative Colitis
  
DOI:
中文关键词: 溃疡性结肠炎  黄芩汤  数据库  临床试验  文献概述
英文关键词: Ulcerative colitis  Huangqin decoction  Database  Clinical trials  Literature review
基金项目:国家自然科学基金项目(编号:82160903);江西省自然科学基金青年基金项目(编号:20212BAB216060); 江西省教育厅科学技术研究项目(编号:GJJ211223);江西省中医药中青年骨干人才(第四批)培养计划项目[赣中医药科教字(2022)7号];江西省中医药管理局科技计划重点项目(编号:2022Z005)
作者单位
陈嘉琪,史秀丽,谢昌营,黄雪云,吴娜 江西中医药大学2022级硕士研究生江西中医药大学附属医院 
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中文摘要:
      目的:检索常用数据库中黄芩汤治疗溃疡性结肠炎(Ulcerative Colitis, UC)的临床试验类文献并进行系统研究,归纳黄芩汤治疗UC的中医证型、用药情况、临床疗效、安全性等,以期为临床治疗提供参考证据。方法:对发表于中国知识基础设施工程(CNKI)、万方数据知识服务平台(Wanfang Database)、中文科技期刊数据库(CCD)和PubMed数据库中黄芩汤治疗溃疡性结肠炎的临床试验类文章进行检索,包括作者姓名、发表时间、样本信息等资料的筛选、抽取;干预措施、临床效果、不良反应等信息的记录。结果:共纳入14篇文献,共计1 076例UC患者。黄芩汤单独或与西医合用能显著改善疗效,并能明显降低不良反应发生率。结论:黄芩汤治疗UC具有较好的疗效和安全性。
英文摘要:
      Objective:To systematically study the clinical trial-type literature on the treatment of ulcerative colitis (UC) with Huangqin decoction published in commonly used databases, and to summarize the chinese medical evidence, drug use, clinical efficacy and safety of Huangqin decoction in the treatment of UC, with a view to providing reference evidence for clinical treatment. Methods: A search was conducted for articles published in the China Knowledge Infrastructure Project (CNKI), Wanfang Data Knowledge Service Platform (Wanfang Database), Chinese Science and Technology Journal Database (CCD) and PubMed database on clinical trials of Huangqin decoction in the treatment of UC, including the screening and extraction of information such as authors' names, publication time and sample information; interventions measures, clinical effects, adverse effects and other information were recorded. Results: A total of 14 articles with a total of 1 076 patients with UC were included in the literature. Huangqin decoction alone or in combination with western medicine significantly improved the overall efficacy and significantly reduced the incidence of adverse effects. Conclusion: Huangqin decoction has good efficacy and safety in the treatment of UC.
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