| 余兴火,高国栋,蒋庄亮,周文俊,江鹰.益气维血颗粒治疗妊娠期缺铁性贫血的临床观察[J].实用中西医结合临床,2022,22(17): |
| 益气维血颗粒治疗妊娠期缺铁性贫血的临床观察 |
| Clinical Observation on Yiqi Weixue Granule in Treating Iron Deficiency Anemia in Pregnancy |
| 投稿时间：2022-09-04 修订日期：2022-09-30 |
| DOI： |
| 中文关键词: 妊娠期贫血 血红蛋白指标 铁蛋白代谢指标 益气维血颗粒 |
| 英文关键词: anemia during pregnancy Hemoglobin index Ferritin metabolism index Yiqi Weixue granule |
| 基金项目: |
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| 中文摘要: |
| 摘要 目的：评估益气维血颗粒辅助治疗妊娠期贫血的疗效及对相关指标的影响。方法：回顾性分析2020年5月~2021年12月在江西省妇幼保健院治疗的90例妊娠期贫血的患者，以治疗方法不同分为观察组和对照组各45例，对照组采用口服铁剂等西药治疗，观察组的患者加用益气维血颗粒治疗，连续用药3个月后,比较两组患者红细胞计数（RBC）、血红蛋白（Hb）、红细胞比容 (HCT) 、红细胞平均体积 (MCV) 、平均红细胞血红蛋白浓度（MCHC）、血清铁蛋白 (SF) 、转铁蛋白饱和度 (TSAT) 、血清铁 (SI)的变化程度以及对妊娠结局的影响。结果：两组治疗后的总有效率分别为93.3%、82%，差异无统计学意义（P>0.05）；观察组患者治疗后Hb、RBC、HCT、MCV、SF、TSAT含量高于对照组，差异有统计学意义（P<0.05）；观察组患者治疗后不良妊娠结局发生率低于对照组，差异有统计学意义（P<0.05）。结论：益气维血颗粒辅助治疗妊娠期缺铁性贫血（DIA）的临床疗效确切，可有效改善贫血指标及铁代谢情况，降低不良妊娠结局发生率，安全性和有效性值得临床推广。 |
| 英文摘要: |
| Abstract：Objective: To evaluate the efficacy of Yiqi Weixue granule in the adjuvant treatment of anemia during pregnancy and its influence on related indexes. Methods: A retrospective analysis was performed on 90 patients with anemia during pregnancy who were treated in Jiangxi Provincial Maternal and Child Health Hospital from May 2020 to December 2021. According to different treatment methods, they were divided into the observation group and the control group, with 45 cases in each group. After 3 months of continuous medication, red blood cell count (RBC), hemoglobin (Hb), specific volume of red blood cell (HCT), mean red blood cell volume (MCV), mean red blood cell hemoglobin concentration (MCHC), serum ferritin (SF), transferrin saturation (TSAT) and serum iron were compared between the two groups (SI) and its impact on pregnancy outcomes. Results: The total effective rates of the two groups after treatment were 93.3% and 82%, respectively, and the difference was not statistically significant (P>0.05); The contents of Hb, RBC, HCT, MCV, SF and TSAT in the observation group after treatment were higher than those in the control group, and the differences were statistically significant (P<.05); The incidence of adverse pregnancy outcomes after treatment in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Yiqi Weixue Granule has definite clinical efficacy in the adjuvant treatment of iron deficiency anemia (DIA) during pregnancy, which can effectively improve anemia indicators and iron metabolism, and reduce the incidence of adverse pregnancy outcomes. The safety and effectiveness of Yiqi Weixue granule are worthy of clinical promotion. |
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