| 何素玲,阮兢.长蛇灸联合电针治疗腹泻型肠易激综合征的临床疗效及对胃肠动力的影响[J].实用中西医结合临床,2022,22(15): |
| 长蛇灸联合电针治疗腹泻型肠易激综合征的临床疗效及对胃肠动力的影响 |
| Clinical efficacy of long snake moxibustion combined with electroacupuncture in the treatment of diarrhea-type irritable bowel syndrome and its effect on gastrointestinal motility |
| 投稿时间：2022-09-02 修订日期：2022-09-14 |
| DOI： |
| 中文关键词: 长蛇灸 电针 腹泻型肠易激综合征 临床疗效 胃肠动力 |
| 英文关键词: Long snake moxibustion electroacupuncture diarrhea-predominant irritable bowel syndrome clinical efficacy gastrointestinal motility. |
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| 中文摘要: |
| 目的 探讨长蛇灸联合电针治疗腹泻型肠易激综合征（IBS-D）的临床疗效及对胃肠动力的影响。方法 按随机数字表法将我院2019年9月-2021年9月期间收治的120例IBS-D患者分为两组（各60例）。对照组用电针治疗，治疗组采取长蛇灸联合电针治疗。观察两组治疗前后IBS病情严重程度量表（IBS-SSS）评分和IBS生活质量量表（IBS-QOL）评分、内脏敏感指数（VSI）评分、肠道菌群数量和胃肠动力指标，分析其疗效与不良反应。结果 与对照组比较，治疗组总有效率更高（96.67％vs 85.00％）（χ2=4.904，P=0.027）；两组治疗后IBS-SSS与VSI评分降低，IBS-QOL评分升高，且相比对照组，治疗组IBS-SSS与VSI评分更低，IBS-QOL评分更高（P<0.05）；治疗后两组肠道菌群数量中双歧杆菌、乳杆菌、拟杆菌均升高，肠球菌数量降低（P<0.05），且相比对照组，治疗组治疗后双歧杆菌、乳杆菌、拟杆菌数量更高，肠球菌数量更低（P<0.05）；治疗后两组血管活性肠肽、胃动素水平降低，且相比对照组，治疗组血管活性肠肽、胃动素更低、P物质水平更高（P<0.05）；治疗组不良反应发生率5.00％，对照组为11.67％，两组比较差异无统计学意义（χ2=1.745，P=0.186）。结论 长蛇灸联合电针治疗IBS-D患者的临床疗效较好，不但能减轻IBS-D症状严重程度，降低患者内脏敏感性，纠正肠道菌群失调，还可促进胃肠激素分泌，提高胃肠动力和生活质量，安全可靠。 |
| 英文摘要: |
| Objective: To explore the clinical efficacy of long snake moxibustion combined with electroacupuncture in the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D) and its effect on gastrointestinal motility. Methods: By random number table, 120 patients with IBS-D admitted to our hospital from September 2019 to September 2021 were divided into two groups (60 cases in each group). The control group was treated with electroacupuncture, while the treatment group was treated with long snake moxibustion combined with electroacupuncture. The IBS disease severity scale (IBS-SSS) score, the IBS quality of life scale (IBS-QOL) score, the visceral sensitivity index (VSI) score, the number of intestinal flora and gastrointestinal motility indexes were observed before and after treatment in the two groups. The efficacy and adverse reactions were analyzed. Results: the total effective rate in treatment group was higher when compared with control group(96.67% vs 85.00%) (χ2=4.904, P=0.027). After treatment, the scores of IBS-SSS and VSI in two groups decreased, and the scores of IBS-QOL increased, and the IBS-SSS and VSI scores of treatment group were lower, and the IBS-QOL score was higher when compared with control group(P<0.05). After treatment, the number of Bifidobacterium, Lactobacillus and Bacteroides in the intestinal flora of the two groups increased, and the number of Enterococcus decreased(P<0.05), and the number of Bifidobacterium, Lactobacillus and Bacteroides in the treatment group was higher and the number of Enterococcus was lower after treatment(P<0.05). After treatment, the levels of vasoactive intestinal peptide and motilin in two groups were decreased, and the levels of vasoactive intestinal peptide and motilin in treatment group were lower, and the level of substance P was higher when compared with control group(P<0.05). The rate of adverse reactions in treatment group was 5.00%, and the control group was 11.67% with no significant difference among two groups(χ2=1.745, P=0.186). Conclusion: Long snake moxibustion combined with electroacupuncture has good clinical efficacy in the treatment of IBS-D patients. It can not only reduce the severity of IBS-D symptoms, reduce the visceral sensitivity of patients, correct intestinal flora imbalance, but also promote gastrointestinal hormone secretion and improve gastric intestinal motility and quality of life with safe and reliable. |
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