| 赵玢,黄仙保,李巧林,郑鹏炜,蓝荣林.灸法治疗中晚期癌症患者癌因性疲乏的系统评价和Meta分析[J].实用中西医结合临床,2022,22(10): |
| 灸法治疗中晚期癌症患者癌因性疲乏的系统评价和Meta分析 |
| Moxibustion in the treatment of Cancer-related Fatigue in patients with advanced cancer: A Systematic Review and Meta-analysis |
| 投稿时间：2022-05-30 修订日期：2022-06-17 |
| DOI： |
| 中文关键词: 灸法 中晚期 癌因性疲乏 系统评价 Meta分析 |
| 英文关键词: Moxibustion Advanced cancer Cancer-related Fatigue Systematic review Meta-analysis |
| 基金项目:江西省教育厅科学技术研究项目(GJJ190655)；江西省卫生健康委技术计划项目(SKJP220202783)；江西中医药大学校级研究生创新专项(编号：JZYC21S67) |
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| 中文摘要: |
| 目的：通过运用Meta分析方法,对目前灸法治疗中晚期癌症患者癌因性疲乏的疗效与安全性做出客观评价。方法：对中国生物医学文献数据库(CBM disc)、中国知网(CNKI)、维普(VIP)、万方(WF)、PubMed、EMBASE、Cochrance Library、Web of Science八大数据库系统展开全面检索,并辅以江西中医药大学图书馆过刊资料库的人工查阅,通过采集灸法治疗中晚期癌症患者癌因性疲乏的随机对照临床试验文献,将检索时间定为各个数据库建库至2022 年 4月 19日,并通过Cochrane偏倚风险评价工具的使用,对已纳入文献展开质量评估,最后再运用 RevMan5.3应用软件展开统计与分析。结果：最终纳入16篇文献,共计1355例病例。Meta分析结果表明：灸法在治疗中晚期癌症患者癌因性疲乏的总有效率、Piper评分量表评分、Karnofsky(卡式)功能状态评分、简易疲乏量表评分、EORTC—QLQ-C30评分方面均比对照组更优。结论: 灸法治疗中晚期癌症患者癌因性疲乏的疗效肯定且安全性真实可信,但仍需更多质量较高、样本数量较大、多中心的随机对照试验进而加以印证。 |
| 英文摘要: |
| Objective: By using the Meta analysis method, this paper objectively evaluates the curative effect and safety of moxibustion in the treatment of cancer-related fatigue in patients with advanced cancer. Methods: A comprehensive search was conducted on eight databases including China Biology Medicine disc (CBM disc), China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), WanFang (WF), PubMed, EMBASE, Cochrance Library, and Web of Science. We collected clinical randomized controlled trials about moxibustion therapy for cancer-related fatigue in patients with advanced cancer and supplemented by manual search of Jiangxi University of Traditional Chinese Medicine Library Past publication database. The retrieval time is set from the establishment of each database to April 19, 2022. And the quality of the included studies was assessed by using the Cochrane Risk of Bias tool. In the end, application software such as RevMan5.3 was used to carry out statistics and analysis. Results: There were 16 Randomized controlled trials, with a total of 1355 cases. The results of Meta-analysis showed that moxibustion was superior than the control group in the total effective rate, Piper score, Karnofsky functional state score, simple fatigue scale and EORTC-QLQ-C30 score in the treatment of cancer-related fatigue in patients with advanced cancer. Conclusion: Moxibustion is effective and safe for cancer-related fatigue in patients with advanced cancer, but it still needs more high-quality, large-sample, multi-center randomized controlled trials to further confirm. |
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