| 吴章明.冠状动脉慢血流患者血栓弹力图特点分析[J].实用中西医结合临床,2022,22(5): |
| 冠状动脉慢血流患者血栓弹力图特点分析 |
| Analysis of the characteristics of thromboelastography in patients with coronary slow flow |
| 投稿时间：2022-02-09 修订日期：2022-03-01 |
| DOI： |
| 中文关键词: 冠状动脉慢血流 血栓弹力图 |
| 英文关键词: coronary slow flow thromboelastography |
| 基金项目:福建省自然科学基金项目 |
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| 中文摘要: |
| 目的：分析冠状动脉慢血流患者血栓弹力图的特点，观察其与冠脉TIMI血流帧数的相关性。方法：回顾2019年01月01日至2021年11月30日于福建中医药大学附属人民医院心血管内科因胸闷、胸痛初次入院的患者2426例，根据入选标准，最终纳入冠状动脉慢血流患者50例为观察组，纳入经冠脉造影检查排除冠心病且无冠脉慢血流的患者50例为对照组。收集两组的一般资料，血栓弹力图、血脂、纤维蛋白原、血小板，观察组的冠脉TIMI血流帧数等资料进行统计学分析。结果：1.两组一般资料比较，观察组吸烟人数18（36%）明显比对照组6（12%）多，差异有统计学意义（P<0.05）；观察组与对照组相比纤维蛋白原、血小板并未明显增加，差异无统计学意义（P>0.05）。2.观察组R、K明显较对照组低，α角、MA观察组均较对照组升高，差异有统计学意义（P<0.05）。3.冠脉平均TIMI血流帧数与血栓弹力图的R、K、α角、MA均无明显相关性，差异无统计学意义（P>0.05）。结论：吸烟患者更容易引起冠状动脉慢血流；有冠状动脉慢血流的患者血液系统呈高凝血因子活性,纤维蛋白原及血小板功能明显增高，处于高血栓风险状态。 |
| 英文摘要: |
| Objective: To analyze the characteristics of thromboelastography in patients with coronary slow flow, and to observe its correlation with coronary TIMI blood flow frame number. Methods: We Reviewed the data of 2426 patients who were initially admitted to the Department of Cardiovascular Medicine, People"s Hospital Affiliated to Fujian University of Traditional Chinese Medicine due to chest tightness and chest pain from January 01, 2019 to November 30, 2021. According to the inclusion criteria, 50 patients with slow coronary blood flow were finally included in the observation group, and 50 patients with coronary heart disease excluded by coronary angiography and without coronary slow flow were included in the control group. The general data , thromboelastography, blood lipids, fibrinogen, platelets of the two groups, and coronary TIMI blood flow frames in the observation group were collected for statistical analysis. Results: 1. Comparing the general data of the two groups, the number of smokers in the observation group 18 (36%) was significantly more than that in the control group 6 (12%), and the difference was statistically significant (P<0.05). There was no significant increase in plasma and platelets, and the difference was not statistically significant (P>0.05). 2. The R and K of the observation group were significantly lower than those of the control group, and the α angle and MA of the observation group were higher than those of the control group, with statistical significance (P<0.05). 3. There was no significant correlation between the mean coronary TIMI blood flow frame number and the R, K, α angle and MA of thrombelastography, and the difference was not statistically significant (P>0.05). Conclusion: Smoking patients are more likely to cause coronary slow flow; patients with coronary slow flow show higher blood coagulation factor activity, significantly increased fibrinogen and platelet functions, and are in a state of high thrombosis risk. |
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