止吐贴联合针刺治疗化疗相关恶心呕吐的临床观察

杨海宁; 李爽; 米硕; 陈科

文章摘要

杨海宁,李爽,米硕,陈科.止吐贴联合针刺治疗化疗相关恶心呕吐的临床观察[J].实用中西医结合临床,2021,21(12):1-3

止吐贴联合针刺治疗化疗相关恶心呕吐的临床观察

Clinical Observation on the Treatment of Chemotherapy-related Nausea and Vomiting with Zhitu Plaster Combined with Acupuncture

DOI：

中文关键词: 化疗相关恶心呕吐针刺止吐贴穴位贴敷

英文关键词: Chemotherapy-induced nausea and vomiting Acupuncture Zhitu plaster Acupoint application

基金项目:北京市医管局培育计划项目（编号：PZ2019012）

作者	单位
杨海宁,李爽,米硕,陈科	北京中医医院顺义医院肿瘤科

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中文摘要:

目的：探讨止吐贴联合针刺治疗患者化疗相关恶心呕吐的临床疗效。方法：选取2018年1月~2020年1月确诊恶性肿瘤需行含顺铂、卡铂或奥沙利铂方案化疗的患者共80例，随机分为AB和BA两组，每组40例。AB组在研究阶段第一周期接受止吐贴联合针刺及盐酸托烷司琼治疗，间隔14~21 d后，下一个周期单用盐酸托烷司琼治疗。BA组治疗顺序与AB组相反。将AB组、BA组中采用止吐贴联合针刺治疗时在统计疗效时统称为治疗组（A组），单纯西药治疗时统称为对照组（B组）。比较A组、B组患者化疗期间恶心、呕吐程度及生活质量评分。结果：A组化疗期间恶心程度明显减低，化疗第1、3、7天缓解程度均优于B组（P＜0.05）；A组化疗第1天呕吐程度明显低于B组（P＜0.05）；A组化疗第1、3天生活质量评分明显优于B组（P＜0.05）。结论：止吐贴联合针刺治疗可明显减轻患者化疗相关恶心呕吐程度，提高患者生活质量。

英文摘要:

Objective: To observe the clinical efficacy of chemotherapy-induced nausea and vomiting treated by Zhitu plaster combined with acupuncture. Methods: 80 Patients with malignant tumor diagnosed from January 2018 to January 2020 were randomly divided into group AB and group BA, 40 cases in each group. Patients in group AB treated by Zhitu plaster combined with acupuncture and tropisetron hydrochloride during the first study cycle, and then treated by tropisetron hydrochloride only during the next cycle after 14~21 days.The order of treatment in group A was reversed to that in group B. Group A (the treatment group) referred to patients who treated by Zhitu plaster combined with acupuncture, while group B (the control group) referred to patients who treated by western medicine treatment only. The degree of the nausea and vomiting, and quality of life scores of patients in group A and group B during the study were compared. Results: The degree of nausea in the group A was significantly decreased during the period of chemotherapy (P＜0.05); the remission degree on the 1st, 3rd and 7th day of chemotherapy was better than that of group B. the degree of vomiting was significantly lower than that in the group B in the first day of chemotherapy (P＜0.05); the quality of life score of the group A was significantly better than that of the group B on the first and third day of chemotherapy (P＜0.05). Conclusion: Zhitu plaster combined with acupuncture can significantly reduce the chemotherapy-induced nausea and vomiting, improve the quality of life of patients.

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