| 刘乔峰.黄葵胶囊联合甘精胰岛素治疗糖尿病肾病的疗效[J].实用中西医结合临床,2021,21(5):1-2,41 |
| 黄葵胶囊联合甘精胰岛素治疗糖尿病肾病的疗效 |
| Effects of Huangkui Capsule Combined with Insulin Glargine in the Treatment of Diabetic Nephropathy |
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| DOI： |
| 中文关键词: 糖尿病肾病 黄葵胶囊 甘精胰岛素 |
| 英文关键词: Diabetic nephropathy Huangkui capsule Insulin glargine |
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| 摘要点击次数: 607 |
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| 中文摘要: |
| 目的：探讨黄葵胶囊联合甘精胰岛素治疗糖尿病肾病的疗效及对患者血尿素氮、血肌酐和尿白蛋白排泄率水平的影响。方法：选取糖尿病肾病患者76例为研究对象，采用抽签方式分为对照组和治疗组，各38例。对照组给予甘精胰岛素治疗，治疗组在对照组基础上口服黄葵胶囊治疗，对比两组临床疗效，治疗前后血糖、肾功能水平和不良反应发生情况。结果：治疗组治疗总有效率明显高于对照组（P＜0.05）；两组空腹血糖、餐后2 h血糖和糖化血红蛋白水平较治疗前显著降低，且治疗组降低程度显著大于对照组（P＜0.05）；两组血尿素氮、血肌酐和尿白蛋白排泄率水平较治疗前明显降低，且治疗组降低程度大于对照组（P＜0.05）；两组不良反应发生情况比较，差异无统计学意义（P＞0.05）。结论：采用黄葵胶囊联合甘精胰岛素治疗糖尿病肾病患者效果显著，能够较好维持患者血糖水平，改善患者肾功能。 |
| 英文摘要: |
| To investigate the effects of Huangkui capsule combined with insulin glycine in the treatment of diabetic nephropathy and their influence on BUN, SCR and UAER levels. Methods: 76 Patients with diabetic nephropathy were selected as the research objects,and they were divided into control group and treatment group by drawing lots method, with 38 cases in each group. The control group was treated with insulin glargine, and the treatment group was treated with Huangkui capsule on the basis of the control group. The clinical efficacy, blood glucose, renal function before and after treatment and the adverse reactions were compared between the two groups. Results: After treatment, the total effective rate of the treatment group was significantly higher than that of the control group (P＜0.05). The levels of blood glucose and glycosylated hemoglobin in the treatment group were significantly lower than those in the control group before treatment, and the degree of reduction in the treatment group was significantly greater than that in the control group (P＜0.05); the levels of blood urea nitrogen, serum creatinine and urinary albumin excretion rate in the two groups were significantly lower than those in the same group before treatment and the degree of reduction in the treatment group was greater than that in the control group (P＜0.05). There was no significant difference in the incidence of adverse reactions between the two groups（P＞0.05）. Conclusion: Huangkui capsule combined with insulin glargine is effective in the treatment of diabetic nephropathy, which can maintain the blood glucose level and improve the renal function. |
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