| 张海燕,李丽,陈小丹.香砂六君子加减治疗急性胰腺炎合并胃肠功能紊乱的临床疗效分析[J].实用中西医结合临床,2020,20(14): |
| 香砂六君子加减治疗急性胰腺炎合并胃肠功能紊乱的临床疗效分析 |
| Clinical efficacy of the addition and subtraction of Xiangsha Liujunzi in the treatment of acute pancreatitis combined with gastrointestinal dysfunction |
| 投稿时间：2020-05-30 修订日期：2020-07-01 |
| DOI： |
| 中文关键词: 香砂六君子加减 急性胰腺炎 胃肠功能紊乱 |
| 英文关键词: : Addition and subtraction of Xiangsha Liujunzi Acute pancreatitis Gastrointestinal dysfunction |
| 基金项目:凉山州科知局科研项目（18YYJS0097） |
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| 中文摘要: |
| 目的 分析香砂六君子加减治疗急性胰腺炎(acute pancreatitis,AP)合并胃肠功能紊乱的临床疗效。 方法 选取本院2018年3月至2020年2月收治且经手术病理或生化指标检测确诊的75例AP合并胃肠功能紊乱患者作为研究对象。根据不同的治疗方法分为对照组和治疗组。比较两组患者临床治疗效果及治疗前后血清白细胞介素-6 ( IL-6)、白介素-8(IL-8)、肿瘤坏死因子-α( TNF-α) 及 C-反应蛋白(CRP)水平变化情况。 结果 治疗组总有效率为93.33%,对照组总有效率为73.00%,低于治疗组(P＜0.05)。治疗后,两组 IL-6、TNF-α及CRP水平均较治疗前降低,且治疗组显著低于对照组(P＜0.05)。 结论 采用香砂六君子加减治疗AP合并胃肠功能紊乱患者效果显著,可改善胃肠功能紊乱,减轻炎症损伤,具有较高的临床应用价值。 |
| 英文摘要: |
| Objective: To analyze the clinical efficacy of the addition and subtraction of Xiangsha Liujunzi in the treatment of acute pancreatitis (AP) combined with gastrointestinal dysfunction. Method: 75 patients with AP combined with gastrointestinal dysfunction who were admitted to our hospital from March 2018 to February 2020 and diagnosed by surgical pathology or biochemical indicators were selected. According to different treatments, they were divided into a control group and a treatment group. The clinical treatment effect and the change in the levels of serum interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP) were compared between the two groups. Results: The total effective rate of the treatment group was 93.33%, and the total effective rate of the control group was 73.00%, which was lower than that of the treatment group (P <0.05).After treatment, the levels of IL-6, TNF-α and CRP in the two groups were lower, and the above levels in the treatment group were significantly lower than those in the control group (P <0.05). Conclusion: The addition and subtraction of Xiangsha Liujunzi in the treatment of patients with AP combined with gastrointestinal dysfunction has a significant effect, and it can improve gastrointestinal dysfunction and reduce inflammation damage, and has higher clinical application value. |
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