| 叶琴飞,张 涛,刘蓓雯.糖尿病性胃轻瘫发病特点及其对患者影响的调查研究[J].实用中西医结合临床,2020,20(6): |
| 糖尿病性胃轻瘫发病特点及其对患者影响的调查研究 |
| Investigation on the characteristics of diabetic gastroparesis and its influence on patients. |
| 投稿时间：2019-12-25 修订日期：2020-04-10 |
| DOI： |
| 中文关键词: 糖尿病 胃轻瘫 血糖控制 |
| 英文关键词: diabetes gastroparesis blood glucose control |
| 基金项目:国家标准化代谢性疾病(糖尿病)管理中心项目(MMC2018） |
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| 摘要点击次数: 1284 |
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| 中文摘要: |
| 目的：探讨糖尿病性胃轻瘫发病特点及其对患者的影响。方法：对我院收治的517例糖尿病患者进行横断面调查，调查对象填写人口统计学问卷、胃轻瘫主要症状指数（Gastroparesis Cardinal Symptoms Index, GCSI）问卷、胃轻瘫对糖尿病相关症状和血糖控制影响的调查问卷。结果：本组糖尿病患者胃轻瘫总体患病率为6.8%（35/517），其中1型糖尿病患者胃轻瘫患病率（13.1%，8/61）显著高于2型糖尿病（5.9%，27/456），差异有统计学意义（P＜0.05）。2型糖尿病患者中，使用二甲双胍控制糖尿病者发生胃轻瘫的比例更高[7.4%（23/310）比2.7%（4/146）]，差异有统计学意义（P＜0.05）。与2型糖尿病患者相比，1型糖尿病患者并发胃轻瘫后对血糖控制的不利影响更大，更容易导致血糖过高、低血糖发作频繁（P＜0.05）。结论：糖尿病尤其是1型糖尿病患者胃轻瘫患病率较高，二甲双胍可能增加胃轻瘫发病风险或者引起胃轻瘫的相似症状，胃轻瘫对1型糖尿病患者血糖控制的不良影响较大。 |
| 英文摘要: |
| Objective: To investigation the characteristics of diabetic gastroparesis and its influence on patients. Methods: A cross-sectional survey was conducted on 517 diabetic patients in our hospital. All the patients completed the demographic questionnaire, the gastroparesis major symptoms index (gcsi) questionnaire, and the questionnaire on the influence of gastroparesis on diabetes related symptoms and blood glucose control. Results: The overall prevalence of gastroparesis in diabetic patients was 6.8% (35 / 517). The prevalence of gastroparesis in type 1 diabetic patients (13.1%, 8 / 61) was significantly higher than that in type 2 diabetic patients (5.9%, 27 / 456), the difference was statistically significant (P < 0.05). Among type 2 diabetic patients, the incidence of gastroparesis was higher in metformin treated patients [7.4% (23 / 310) vs 2.7% (4 / 146)], the difference was statistically significant (P < 0.05). Compared with patients with type 2 diabetes, gastroparesis in type 1 diabetes have more adverse effects on blood glucose control, which is more likely to lead to hyperglycemia and frequent hypoglycemia (P < 0.05). Conclusion: The prevalence of gastroparesis is high in diabetes, especially in type 1 diabetes. Metformin may increase the risk of gastroparesis or cause similar symptoms of gastroparesis. Gastroparesis has a greater adverse effect on blood glucose control in type 1 diabetes. |
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