| 熊万宇,梁志清.2型糖尿病并发抑郁症的危险因素及胰岛素干预和抑郁程度关系的研究[J].实用中西医结合临床,2019,19(11): |
| 2型糖尿病并发抑郁症的危险因素及胰岛素干预和抑郁程度关系的研究 |
| The risk factors of depression associated with type 2 diabetes mellitus and the relationship between insulin intervention and depression degree |
| 投稿时间：2019-08-02 修订日期：2019-08-18 |
| DOI： |
| 中文关键词: 2型糖尿病 抑郁症 抑郁量表 胰岛素 |
| 英文关键词: Type 2 diabetes Depression Depression Scale Insulin |
| 基金项目: |
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| 中文摘要: |
| 摘要：【目的】探讨2型糖尿病（Type 2 diabetes mellitus，T2DM）并发抑郁的独立危险因素及胰岛素治疗对抑郁程度的影响。【方法】根据抑郁量表评分将299例T2DM患者分为抑郁组和非抑郁组，抑郁症组再根据治疗方式分为非胰岛素干预组和胰岛素干预组。【结果】299例患者中发生抑郁159例（53.18%），未并发抑郁140例（46.82%）。糖尿病并发抑郁与糖化血红蛋白（OR=2.680）、年龄（OR=2.431）、女性（OR=3.055）、糖尿病合并症数目（OR=1.802）显著相关。胰岛素治疗组比非胰岛素治疗组抑郁程度轻。【结论】年龄、女性、糖化血红蛋白、糖尿病合并症数是T2DM并发抑郁的危险因素。存在胰岛素治疗适应症的T2DM患者需尽早使用胰岛素控制病情。 |
| 英文摘要: |
| Abstract: [Objective] To investigate the risk factors of depression associated with type 2 diabetes mellitus(Type 2 diabetes mellitus，T2DM) and the effect of insulin therapy on depression. [Methods] According to the Depression scale, 299 T2DM patients were divided into depression group and non-depression group. The depression group was divided into non-insulin intervention group and insulin intervention group according to the treatment method. [Results] There were 159 cases(53.18 %) of depression in 299 patients and 140 cases(46.82 %) of depression. Diabetes concurrent depression is significantly related to glycosylated hemoglobin(OR = 2.680), age(OR= 2.431), women(OR = 3.055), and the number of diabetes complications(OR = 1.802). Insulin therapy group was less depressed than non-insulin therapy group. [Conclusion] Age, women, glycosylated hemoglobin, and diabetes complications are risk factors for T2DM concurrent depression. Patients with T2DM who have insulin therapy indications need to use insulin as early as possible to control the condition. |
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