| 李康,崔可新,敖放,唐珺洋,王一行,李跃飞.神经根型颈椎病中药临床用药规律研究[J].实用中西医结合临床,2019,19(10): |
| 神经根型颈椎病中药临床用药规律研究 |
| Study on the law of clinical application of traditional Chinese medicine in cervical spondylotic radiculopathy |
| 投稿时间：2019-05-30 修订日期：2019-08-14 |
| DOI： |
| 中文关键词: 神经根型颈椎病 中药 用药规律 关联规则 特点分析 |
| 英文关键词: Cervical Spondylotic Rradiculopathy Traditional Chinese medicine Drug law Association rules Characteristics analysis |
| 基金项目: |
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| 摘要点击次数: 1157 |
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| 中文摘要: |
| 目的：探讨中药临床治疗神经根性颈椎病(Cervical Spondylotic Rradiculopathy,CSR)的用药规律。方法：以中国知网检索及分析系统作为数据信息来源,以中药“神经根型颈椎病”合并“中药”或“中医”为主题进行检索,搜索2010年1月1日-2019年5月1日,纳入文献记载临床治疗中药方剂,建立数据库,进行统计分析。使用Excel 2013、SPSSSModelerS14.1、SPSS Statistics 19.0统计软件对纳入的中药进行关联规则分析。结果：纳入符合标准的文献402篇,279味中药,累积频率6121次。频数＞45的中药共39种。39味中药的功效分类中,以活血化瘀药、补虚药和解表药的使用频率最多；药性味中,药味以辛、苦、甘最多,药性以温、平、寒最多；归经分类中,以肝、脾、心经最多。关联规则分析中发现关联强度最高的药对组合为33种,因子分析中提取7个公因子。结论：中医药治疗CSR多以活血化瘀药、补虚药、解表药、祛风湿药为主,基本与其常见证型气滞、寒湿、血瘀和痰湿相吻合,对指导临床用药具有一定的指导意义。 |
| 英文摘要: |
| Objective:To investigate the law of Chinese medicine in the clinical treatment of cervical spondylotic radiculopathy.Methods:The retrieval and analysis system of cnki was used as the data information source,to search for the Chinese medicine "nerve root type cervical spondylosis" with the theme of "Chinese medicine" or "Chinese medicine",From January 1, 2010 to May 1, 2019, TCM prescriptions for clinical treatment recorded in literature were collected, and a database was established for statistical analysis.Excel 2013, SPSS Modeler 14.1, and SPSS Statistics 19.0 were used to analyze the association rules of the included TCM.Result:A total of 402 articles, 279 Chinese herbal medicines and 6121 cumulative frequency were included. There are 39 kinds of traditional Chinese medicines with frequency of > 45. In the efficacy classification of 39 kinds of traditional Chinese medicines, the most frequently used drugs are those for activating blood circulation and removing blood stasis, tonifying deficiency and relieving superficial symptoms.Among the medicinal properties, the most bitter, bitter and sweet were in the medicinal properties, and the most mild, even and cold were in the medicinal properties. Liver, spleen and heart are the most common classifications.In association rule analysis, 33 combinations of drug pairs with the highest association strength were found, and 7 common factors were extracted from factor analysis. Conclusion:Traditional Chinese medicine (TCM) mainly treats CSRS with drugs for promoting blood circulation and removing blood stasis, tonifying deficiency, clearing the surface and removing wind and dampness.It is basically consistent with the common syndromes of qi stagnation, cold dampness, blood stasis and phlegm dampness, and has certain guiding significance for clinical medication. |
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