步晓筠,杨洁,刘建成,邵峰,毛小尹.银川地区临床血型不规则抗体检测和分析[J].实用中西医结合临床,2019,19(10): |
银川地区临床血型不规则抗体检测和分析 |
Prevalence and Specificity of irregular RBC antibodies in Patients from Yinchuan |
投稿时间:2019-05-10 修订日期:2019-07-03 |
DOI: |
中文关键词: 血型 不规则抗体 银川 |
英文关键词: blood group irregular antibody Yinchuan |
基金项目: |
|
摘要点击次数: 908 |
全文下载次数: 292 |
中文摘要: |
目的 通过对银川地区临床标本检测结果的分析,了解银川患者人群中各种不规则抗体的检出频率及分布特点。方法 应用盐水、抗球蛋白法、微柱凝胶法结合谱细胞确定不规则抗体的特异性。结果 从9244例临床标本中鉴定确认血型不规则抗体77例,其中Rh血型系统不规则抗体73例。60例不规则抗体来自孕妇或新生儿血样,抗D(42例)>抗E(10例);其余17例来自各种疾病配血患者,抗E(9例)>抗D(1例)。结论 检出不规则抗体以Rh血型系统分布最多,孕妇与配血患者不规则抗体分布明显不同,妊娠及输血免疫刺激是Rh血型系统抗体产生的主要原因。 |
英文摘要: |
Objective A retrospective study was performed to estimate the frequency and specificity of clinically significant irregular RBC antibodies of patients in Yinchuan. Methods Irregular antibody testing was carried out by brine, anti-human-globulin and microcolulmn gel test methods.Results A total of 77 samples containing specific irregular antibodies were found among 9244 patients in Yinchuan. Anti-Rh antibodies were identified in 73 patients.60 samples of irregular antibodies were identified from pregnant or neonatal patients, anti-D (42samples)>anti-E(10samples); other 17 samples of irregular antibodies were identified from pretransfusion cross-matching patients, anti-E (9samples)>anti-D(1samples). Conclusion The frequencies of Rh antibodies is significantly higher than irregular antibodies of other blood group. Of all the anti-Rh antibodies , anti-D is the most frequently identified in pregnant or neonatal patients, while anti-E is the most frequently identified in pretansfusion cross-matching patients. Alloimmunization by pregnancy and transfusion constitute the major causes of anti-Rh alloantibodies. |
查看全文
查看/发表评论 下载PDF阅读器 |
关闭 |
|
|
|