| 袁钰荔，尹玉月，范惠珍.DAS28-CRP与DAS28-ESR评分在类风湿关节炎中的比较[J].实用中西医结合临床,2018,18(11):5-6,9 |
| DAS28-CRP与DAS28-ESR评分在类风湿关节炎中的比较 |
| Comparative Analysis of DAS28-CRP and DAS28- ESR Disease Activity Scores in the Evaluation of Rheumatoid Arthritis Diseases |
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| DOI： |
| 中文关键词: 类风湿关节炎 C反应蛋白 血沉 DAS28 相关性分析 |
| 英文关键词: Rheumatoid arthritis C-reactive protein Erythrocyte sedimentation rate DAS28 Comparative Analysis |
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| 中文摘要: |
| 摘要：目的：探究C反应蛋白和红细胞沉降率两种DAS28评分方法在评估类风湿关节炎患者疾病活动方面的关系。方法：采用回顾性分析，观察2017年1~12月在宜春市人民医院在我院住院治疗的69例RA患者，记录分析患者的临床资料，分别计算他们的DAS28-ESR和DAS28-CRP两种评分，采用Pearson’s相关分析分析两种评分方法之间的关系，比较两种评分的分布差异以及两种评分与患者资料之间的关系。结果：DAS28-ESR与DAS28-CRP评分具有很好的线性关系，且有统计学意义（y= 0.771x+1.805，r=0.821，P＜0.001），DAS28-CRP评分（4.73±1.01）分，低于DAS28-ESR评分（5.45±0.95）分，二者的差异有统计学意义（P＜0.001）。结论：DAS28-ESR与DAS28-CRP两种评分方法在评价RA患者疾病活动度时虽有相关关系却也有显著差异，可能会影响医生对RA患者病情的评估和治疗用药的选择，应予以关注。 |
| 英文摘要: |
| Abstract: Objective: To investigate the two DAS28 scoring methods for C-reactive protein (CRP) and Erythrocyte sedimentation rate (ESR) in the evaluation of rheumatoid arthritis (RA). The relationship between the patient's disease activity. Methods: A retrospective study was performed to observe 69 patients with RA in our hospital. The clinical data of the patients were recorded and analyzed. The scores of DAS28-ESR and DAS28-CRP were calculated respectively. Pearson and s correlation analysis were used to analyze the relationship between the two. Results: The DAS28-ESR had a good linear relationship with the DAS28-CRP score, and was statistically significant (y=0.771x+1.805, r=0.821, P＜0.001). The DAS28-CRP score (4.73±1.01) was lower than DAS28-ESR score (5.45 ± 0.95), the difference was statistically significant (P＜0.001). Conclusion: DAS28-ESR and DAS28-CRP scoring methods have significant correlations when evaluating patients' disease activity, but they should also be concerned. |
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