| 袁钰荔,尹玉月,范惠珍.DAS28- CRP与DAS28- ESR两种疾病活动评分在类风湿关节炎疾病评估中的比较分析[J].实用中西医结合临床,2018,18(11): |
| DAS28- CRP与DAS28- ESR两种疾病活动评分在类风湿关节炎疾病评估中的比较分析 |
| Comparative analysis of DAS28-CRP and DAS28- ESR disease activity scores in the evaluation of rheumatoid arthritis diseases |
| 投稿时间：2018-08-28 修订日期：2018-08-28 |
| DOI： |
| 中文关键词: C反应蛋白 血沉 DAS28 类风湿关节炎 比较 |
| 英文关键词: C-reactive protein Erythrocyte sedimentation rate Disease activity score Rheumatoid arthritis Comparison |
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| 中文摘要: |
| 目的 探究C反应蛋白(C-reactive protein ,CRP)和红细胞沉降率(Erythrocyte sedimentation rate ,ESR)的两种DAS28(Disease activity score,DAS)评分方法在评估类风湿关节炎(Rheumatoid arthritis,RA)患者疾病活动方面的关系。方法 采用回顾性研究方法,观察我院住院治疗的69例RA患者,记录分析患者的临床资料,分别计算DAS28-ESR和DAS28-CRP两种评分,采用Pearson,s相关分析分析两种评分方法之间的关系、比较两种评分的分布差异以及两种评分与患者资料之间的关系。结果 DAS28-ESR与DAS28-CRP评分具有很好的线性关系,且有统计学意义(y=0.771x+1.805, r=0.821, P<0.001),DAS28-CRP评分(4.73±1.01)低于DAS28-ESR评分(5.45±0.95),二者的差异有统计学意义(P<0.001)。结论 DAS28-ESR与DAS28-CRP两种评分方法在评价患者疾病活动度时虽有相关关系却也有显著差异,可能会影响医生对RA患者病情的评估和治疗用药的选择,应予以关注。 |
| 英文摘要: |
| Objective To investigate the two DAS28 (Disease activity score (DAS) scoring methods for C-reactive protein (CRP) and Erythrocyte sedimentation rate (ESR) in the evaluation of rheumatoid arthritis (RA). The relationship between the patient"s disease activity. Methods A retrospective study was performed to observe 69 patients with RA in our hospital. The clinical data of the patients were recorded and analyzed. The scores of DAS28-ESR and DAS28-CRP were calculated respectively. Pearson and s correlation analysis were used to analyze the relationship between the two. Relationship and distribution differences and relationships with patient data. Results The DAS28-ESR had a good linear relationship with the DAS28-CRP score, and was statistically significant (y=0.771x+1.805, r=0.821, P<0.001). The DAS28-CRP score (4.73±1.01) was lower than DAS28. The -ESR score (5.45 ± 0.95), the difference between the two was statistically significant (P < 0.001). Conclusion DAS28-ESR and DAS28-CRP scoring methods have significant correlations when evaluating patients" disease activity, but they should also be concerned. |
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