| 邓红梅,晏宁.阿尔茨海默病与睡眠障碍共病机制的研究进展[J].实用中西医结合临床,2019,19(1): |
| 阿尔茨海默病与睡眠障碍共病机制的研究进展 |
| Advances in the co-pathogenesis of Alzheimer''s disease and sleep disorders |
| 投稿时间：2018-08-14 修订日期：2018-08-25 |
| DOI： |
| 中文关键词: 阿尔茨海默病 睡眠障碍 |
| 英文关键词: Alzheimer Disease Sleep Wake Disorders |
| 基金项目: |
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| 中文摘要: |
| 阿尔茨海默病（Alzheimer''s disease，AD），又叫老年性痴呆，是一种严重的神经退行性疾病，起病隐袭，病程呈慢性进行性，是老年期痴呆最常见的一种类型。主要表现为渐进性记忆障碍、认知功能障碍、人格改变及语言障碍等神经精神症状，严重影响社交、工作与生活能力，每年导致数千亿美元的健康支出。睡眠障碍不仅是AD的常见症状，而且是导致AD发生的重要诱因。改善睡眠障碍可能会改变AD的进程，同时将极大的减轻患者及社会的负担。本文将对睡眠障碍与AD关系的研究进展进行综述 |
| 英文摘要: |
| Alzheimer''s disease (AD), also known as senile dementia, is a serious neurodegenerative disease with hidden onset and slow course, which is the most common type of senile dementia.It is mainly manifested as progressive memory disorder, cognitive disorder, personality change, language disorder and other neuropsychiatric symptoms, which even affect the ability to live, work and socialize. It is a huge health expenditure every year.Sleep disorder is not only a common symptom of AD, but also an important cause of AD.Improving sleep disorders may change the course of AD and greatly reduce the burden on patients and society.This paper reviews the research progress of the relationship between sleep disorder and AD. |
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