| 李含章.健脾通腑方序贯联合生长抑素治疗急性胰腺炎对TREM-1水平和胰腺功能的影响分析[J].实用中西医结合临床,2018,18(10): |
| 健脾通腑方序贯联合生长抑素治疗急性胰腺炎对TREM-1水平和胰腺功能的影响分析 |
| Effect of Jianpi Tongfu Formula combined with somatostatin on TREM-1 level and Pancreatic function in Acute pancreatitis |
| 投稿时间：2018-06-23 修订日期：2018-06-29 |
| DOI： |
| 中文关键词: 健脾通腑方 生长抑素 急性胰腺炎 髓样细胞触发受体-1 胰腺功能 |
| 英文关键词: Jianpi Tong Fu recipe somatostatin Acute pancreatitis Myeloid Cell trigger receptor -1 Pancreatic function |
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| 中文摘要: |
| 【】目的 分析健脾通腑方序贯联合生长抑素治疗急性胰腺炎对髓样细胞触发受体-1(TREM-1)水平和胰腺功能的影响。方法 回顾性选取2015年12月至2018年1月我院收治的急性胰腺炎患者106例,根据治疗方法不同分为对照组和观察组。对照组患者采用常规治疗联合生长抑素治疗,观察组患者加用健脾通腑方序贯治疗,分析两组患者治疗后的临床效果。结果 治疗前,两组患者中医症状积分水平比较,差异无统计学意义(P>0.05)。治疗后,观察组患者中医症状积分水平低于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者TREM-1、内皮素(ET)、C反应蛋白(CRP)、胰腺功能指标水平比较,差异无统计学意义(P>0.05)。治疗后,观察组患者正铜蓝蛋白(CP)、胰岛素(INS)水平高于对照组,TREM-1、ET、CRP、胰蛋白酶原-2(TPS-2)、脂肪酶(LIP)水平低于对照组,差异有统计学意义(P<0.05)。观察组患者中转手术率低于对照组,血淀粉酶恢复时间、腹痛缓解时间及住院时间短于对照组,差异有统计学意义(P<0.05)。结论 健脾通腑方序贯联合生长抑素治疗急性胰腺炎可降低患者TREM-1、ET、CRP水平,改善患者胰腺功能,缩短住院时间。 |
| 英文摘要: |
| Objective To analyze the effect of Jianpi Tongfu prescription combined with somatostatin in the treatment of acute pancreatitis on myeloid cell trigger receptor - 1 ( TREM - 1 ) level and pancreatic function .Methods 106 patients with acute pancreatitis from December 2015 to January 2018 were retrospectively selected and divided into control group and observation group according to different treatment methods. The patients in the control group were treated with routine therapy combined with somatostatin, and the patients in the observation group were treated with Jianpi Tongfu recipe. The clinical effect of the two groups was analyzed.Results Before treatment, there was no significant difference in TCM symptom score between the two groups (P > 0.05). After treatment, the level of TCM symptom score in the observation group was lower than that in the control group (P < 0.05). Before treatment, there was no significant difference in the levels of TREM-1 ETCRP and pancreatic function between the two groups (P > 0.05). After treatment, the level of CPN ins in the observation group was significantly higher than that in the control group (P < 0.05). Observation group The conversion rate of the patients was lower than that of the control group, and the recovery time of serum amylase, the time of abdominalgia relief and the time of hospitalization were shorter than those of the control group (P < 0.05).Conclusion Jianpi Tongfu recipe combined with somatostatin can reduce the level of TREM-1ETT CRP, improve pancreatic function and shorten hospitalization time in patients with acute pancreatitis. |
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