文章摘要
黄建生 黄文丽 曾昭笔.对高热患者行安脑丸与对乙酰氨基酚的效果对比[J].实用中西医结合临床,2018,18(2):130-132
对高热患者行安脑丸与对乙酰氨基酚的效果对比
The Effect Comparison of Annao Pills and Acetaminophen in Treating Patients with High Fever
  
DOI:
中文关键词: 高热  安脑丸  对乙酰氨基酚
英文关键词: High fev er  Annao pill  Acetaminophen  Efficacy
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作者单位
黄建生 黄文丽 曾昭笔 广东省东莞市虎门镇社区卫生服务中心 广东省东莞市太平人民医院 
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中文摘要:
      目的:探讨高热患者采取安脑丸与对乙酰氨基酚治疗的效果。方法:选择我社区服务中心接诊的高热患者160例进行研究,入组时间2015年8月~2017年5月,纳入对象愿意配合本研究,以随机数表法分为安脑丸组与对乙酰氨基酚组,每组80例。安脑丸组患者接受安脑丸治疗,对乙酰氨基酚组患者采取对乙酰氨基酚治疗,对两组患者用药前、用药0.5 h、用药1 h、用药2 h、用药4 h时体温进行记录,评价两组退热效果,并随访1个月统计高热复发情况,统计学分析两组指标。结果:两组患者在用药前体温无差异(P>0.05),用药0.5 h与用药4 h时体温也无差异(P>0.05),但用药1 h、用药2 h时对乙酰氨基酚组体温显著低于安脑丸组(P<0.05);两组患者退热效果比较无差异(P>0.05);随访1个月,安脑丸组高热复发1例,而对乙酰氨基酚组高热复发12例,比较差异有统计学意义(P<0.05)。结论:安脑丸与对乙酰氨基酚应用在高热患者中均可取得不错的退热效果,但对乙酰氨基酚起效更快,而安脑丸起效慢,作用更持久,不易反弹,二者各有优劣,临床可合理选择。
英文摘要:
      Objective: To investigate the efficacy of Annao pills and Acetaminophen in treating patients with high fever. Methods: 160 Patients with high fever admitted to our community service center from August 2015 to May 2017 were selected. The included objects were willing to cooperate in this study, and were divided into Annao pill group and Acetaminophen group by using the random number table method, with 80 cases in each group. Patients in the Annao pill group received Annao pill treatment, and the Acetaminophen group received acetaminophen treatment. The body temperatures of patients in the two groups before treatment and 0.5 h, 1 h, 2 h and 4 h after treatment were recorded, the effect of abatement of fever was evaluated, and the recurrence of high fever within 1 month was statistically analyzed. Results: There was no difference in the body temperature between the two groups before treatment (P>0.05), and between 0.5 h and 4 h after drug medication (P>0.05), but at 1 h and 2 h after drug medication, the body temperature in the Acetaminophen group was significantly lower than that in the Annao pill group (P<0.05); there was no difference in the effect of abatement of fever between the two groups (P>0.05); after 1 month of follow-up visit, 1 case and 12 cases respectively in Annao pill group and Acetaminophen group had recurrence of high fever, and the difference was statistically significant (P<0.05). Conclusion: Both Annao pill and Acetaminophen can achieve favorable antipyretic effect when used in patients with high fever, but Acetaminophen has faster effect onset, Annao pill has slow effect onset and more lasting effect and it is not easy to rebound. So the two drugs have their respective advantages and disadvantages, they should be reasonably chosen in clinic.
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