| 陈青青 王新艳 范惠珍 袁芸 余晚婷 李莫娴.理气暖胃颗粒对肝胃不和挟寒型慢性浅表性胃炎患者CCK、NPY表达的影响[J].实用中西医结合临床,2017,17(5):1-3 |
| 理气暖胃颗粒对肝胃不和挟寒型慢性浅表性胃炎患者CCK、NPY表达的影响 |
| The Influence of Liqinuanwei Granule for CSG of Liver- Stomach Disharmony with Cold Syndrome on CCK, NPY |
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| DOI： |
| 中文关键词: 慢性浅表性胃炎 理气暖胃颗粒 胆囊收缩素 神经肽Y |
| 英文关键词: Chronic superficial gastritis Liqinuanwei granule CCK NPY |
| 基金项目: |
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| 中文摘要: |
| 目的：观察理气暖胃颗粒治疗肝胃不和挟寒型CSG的临床疗效，并探讨可能的作用机制。方法：119例肝胃不和挟寒型CSG患者服用理气暖胃颗粒，1袋/次，3次/d，疗程为4周。观察治疗前、中、后症状及体征，同时检测治疗前后血清CCK、NPY水平。结果：理气暖胃颗粒治疗肝胃不和挟寒型CSG的总有效率为87.85%；治疗后患者血清CCK水平较治疗前有所下降（P＜0.05），NPY水平明显上升（P＜0.05）。结论：理气暖胃颗粒治疗肝胃不和挟寒型CSG疗效明显，其部分机制可能与降低血清CCK、升高NPY水平有关。 |
| 英文摘要: |
| Objective: To observe the clinic efficacy and its mechanism of the method of Liqinuanwei granule in the treatment of chronic superficial gastritis (CSG) of liver-stomach disharmony with cold syndrome. Method: 119 Cases of CSG of liver-stomach disharmony with cold syndrome, were treated with Liqinuanwei granule for 4 weeks. The changes of the clinical symptom and sign were observed before and after treatment, and the contents of CCK and NPY in serum were measured. Result: The total effectiveness was 87.85%, compared with pre-treatment, the CCK in all patients of post-treatment were significantly lower (P＜0.05), and the NPY significantly increased (P＜0.05). Conclusion: Liqinuanwei granule in treating CSG of liver-stomach disharmony with cold syndrome may decrease the content of serum CCK and increase NPY, and thus improve the clinical symptoms. |
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