损伤胶囊联合依降钙素治疗绝经后骨质疏松症的疗效观察

雷宁波; 董林; $2; $2; $2; 彭冉东

文章摘要

雷宁波董林邢涛赵军张磊彭冉东.损伤胶囊联合依降钙素治疗绝经后骨质疏松症的疗效观察[J].实用中西医结合临床,2017,17(4):1-3,67

损伤胶囊联合依降钙素治疗绝经后骨质疏松症的疗效观察

The Clinical Efficacy Observation of Injury Capsule Combined with Elcatonin in the Treatment of Postmenopausal Osteoporosis

DOI：

中文关键词: 绝经后骨质疏松症损伤胶囊依降钙素

英文关键词: Postmenopausal Osteoporosis Injury Capsule Elcatonin Clinical Efficacy

基金项目:甘肃省中医药管理局项目（编号：GZK-2014-10）

作者	单位
雷宁波董林邢涛赵军张磊彭冉东	甘肃省中医院；甘肃中医药大学

摘要点击次数: 877

全文下载次数: 251

中文摘要:

目的：观察损伤胶囊联合依降钙素治疗绝经后骨质疏松症的临床疗效。方法：将2013年6月~2015年3月我科收治的绝经后骨质疏松患者72例随机分为两组，每组36例。观察组给予我院制剂损伤胶囊口服配合依降钙素肌注治疗，对照组单纯给予依降钙素肌注，对所有患者均进行不少于1年的随访。采用视觉模拟疼痛评分（Visual Analogue Scale，VAS）及Oswestry功能障碍指数（Oswestry Dability Index，ODI）对两组患者腰背部疼痛、活动功能进行评估；采用双能X线骨密度仪（DXA）测量腰椎（L2~4）骨密度值（BMD）；行腰/胸椎正侧位检查，观察两组骨折发生率。定期对患者随访，记录相关测量数据。结果：两组治疗后3个月腰背部疼痛及功能障碍均缓解，但对照组治疗后6个月、末次随访时VAS评分及ODI指数均高于观察组（P＜0.05）。末次随访，观察组与对照组骨密度T值分别为（－2.01±0.680）、（－2.24±0.023），差异有统计学意义（P＜0.05）。两组骨折发生率为对照组22.3%、观察组5.6%，差异有统计学意义（P＜0.05）。结论：损伤胶囊联合依降钙素可有效减轻因骨质疏松进行性加重导致的腰背痛、提高骨密度，同时损伤胶囊可降低早期骨折的发生率，预防骨质疏松骨折，提高临床疗效。

英文摘要:

Objective: To observe the clinical efficacy of Injury capsule combined with elcatonin in the treatment of postmenopausal osteoporosis. Methods: From June 2013 to March 2013, 72 patients with postmenopausal osteoporosis in our hospital were randomly divided into control group and observation group, each group with 36 patients. The observation group received the hospital preparation injury capsule combined with elcatonin injection therapy; the control group only treated with elcatonin injection. Assessed the degree of pain in the waist and back of the two groups by visual analogue scale (VAS); and the active function of the two groups were assessed by the oswestry dability index (ODI); measured the bone mineral density (BMD) of lumbar vertebra (L2~4) by dual energy X-ray absorptiometry (DXA); and scanned the lumbar / thoracic right lateral to observe the fracture rate of the two groups. Followed all patients with more than 1 years regularly, recorded the related data. Results: 3 months after the treatment, the lumbar back pain and the dysfunction of the two groups were relieved;6 months after the treatment and at the end of the follow-up, the VAS score and ODI index of the control group were higher than those of the observation group, the difference was statistically significant, P＜0.05; at the end of the follow-up, the T value of bone mineral density of the observation group and the control group were (－2.01+0.680) and (－2.24+0.023), the difference was statistically significant, P＜0.05; the incidence of fracture the observation group was 5.6% less than 22.3% in the control group, the difference was statistically significant, P＜0.05. Conclusion: The injury capsule combined with elcatonin can effectively reduce the degree of pain in the waist and back caused by progressive exacerbation of osteoporosis, increase bone density, reduce early the incidence of fracture, prevent fractura caused by postmenopausal osteoporosis, the clinical efficacy is remarkable.

查看全文查看/发表评论下载PDF阅读器

关闭