文章摘要
陈青青,王新艳,范惠珍,袁芸,余晚婷,李莫娴.理气暖胃颗粒对肝胃不和挟寒型慢性浅表性胃炎患者CCK、NPY表达的影响[J].实用中西医结合临床,2017,17(5):
理气暖胃颗粒对肝胃不和挟寒型慢性浅表性胃炎患者CCK、NPY表达的影响
The Influence of Liqinuanwei Granule for CSG of Liver- stomach Disharmony with Cold Syndrome on CCK,NP Y
投稿时间:2017-03-04  修订日期:2017-04-20
DOI:
中文关键词: 理气暖胃颗粒  慢性浅表性胃炎  胆囊收缩素  神经肽Y
英文关键词: Liqinuanwei granule  chronic superficial gastritis  CCK  NPY
基金项目:
作者单位E-mail
陈青青 宜春学院 853713564@qq.com 
王新艳 宜春学院  
范惠珍* 宜春市人民医院暨宜春学院临床医学院 fanfanyc@163.com 
袁芸 宜春学院  
余晚婷 宜春学院  
李莫娴 宜春学院  
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中文摘要:
      目的 观察理气暖胃颗粒治疗肝胃不和挟寒型CSG的临床疗效,并探讨可能的作用机制。方法 119例肝胃不和挟寒型CSG患者服用理气暖胃颗粒,一次1袋,一日3次,疗程为4周。观察治疗前、中、后症状及体征,同时检测治疗前后血清CCK、NPY水平。结果 理气暖胃颗粒治疗肝胃不和挟寒型CSG的总有效率为87.85%;治疗后患者血清CCK水平有所下降 (P<0.05),NPY水平明显上升 (P<0.05)。结论 理气暖胃颗粒治疗肝胃不和挟寒型CSG疗效明显,其部分机制可能与降低血清CCK、升高NPY水平有关。
英文摘要:
      Objective To observe the clinic efficacy and its mechanism of the method of Liqinuanwei granule in the treatment of chronic superficial gastritis of liver- stomach disharmony with cold syndrome. Method 119 cases of patients,conforming to the diagnostic criteria of chronic superficial gastritis of liver- stomach disharmony with cold syndrome,were chosen from the Digestive outpatient department of Internal Medicine and treated with Liqinuanwei granule for 4 weeks. The changes of the clinical symptom and sign were observed before and after treatment. Besides,the contents of CCK and NPY in serum were measured. Result The total effectiveness is 87.85%, compared post-treatment with pre-treatment,the CCK in all patients was significantly lower (P<0.05) and the NPY significantly increased (P<0.05). Conclusion Liqinuanwei granule in treating CSG of liver-stomach disharmony with cold syndrome may decrease the content of serum CCK and increase NPY,and thus improve the clinical symptoms.
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