| 邱冬妮,黄闰月,谭希.强直性脊柱炎合并骨质疏松症的病因和影像学研究进展[J].实用中西医结合临床,2016,16(12): |
| 强直性脊柱炎合并骨质疏松症的病因和影像学研究进展 |
| Etiology and progress in imaging diagnosis of osteoporosis in ankylosing spondylitis |
| 投稿时间：2016-10-21 修订日期：2016-11-21 |
| DOI： |
| 中文关键词: 强直性脊柱炎,骨质疏松,病因,影像 |
| 英文关键词: anklosing spondilitis osteoporosis etiology imaging |
| 基金项目:国家自然科学基金(81273736) |
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| 中文摘要: |
| 【】骨质疏松症(osteoporosis,OP)同异位骨化一样,已成为强直性脊柱炎(ankylosing spondylitis,AS) 的共同特征。由于炎症反应引发破骨活动增强,患者早期即可出现骨质疏松,此外关节强直导致的脊柱活动性降低及疾病活动程度等因素也有相关。AS患有骨质疏松症和骨折的高风险,病程越长,风险越高,可导致脊柱骨折、后凸畸形及神经功能损害等并发症,严重影响患者生活质量。本文就近年来AS患者骨质疏松的病因学及影像学诊断进展进行综述。 |
| 英文摘要: |
| Osteoporosis and heterotopic ossification are now well recognized the common features in patients with anklosing spondylitis.Osteoclasts activity increasing, caused by the inflammatory response in patients with early stage of osteoporosis, and joint stiffness in the spine decreased activity and factors are associated with the degree of disease activity.There is high incidence of osteoporosis in AS patients,which can cause especially spine fracture、kyphosis and neumological impairment which affect quality of life of the patients seriously in the early and mid-term of the disease.This paper reviews the osteoporosis etiology in AS patients and summarized progress in imaging diagnosis. |
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