| 王小青,王剑,赵诗云,吴东风,刘丹.穿心莲内酯对小鼠早期感染性休克的影响[J].实用中西医结合临床,2016,16(8): |
| 穿心莲内酯对小鼠早期感染性休克的影响 |
| Effect of andrographolide on mice of early septic shock#$NBS |
| 投稿时间：2016-08-18 修订日期：2016-08-29 |
| DOI： |
| 中文关键词: 穿心莲内脂 小鼠 感染性休克模型 内毒素 |
| 英文关键词: |
| 基金项目: |
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| 中文摘要: |
| 目的：建立感染性休克小鼠动物模型后,观察穿心莲内脂对早期感染性休克小鼠的影响。方法：采用小鼠腹腔注射内毒素(LPS)造成感染性休克模型,观察穿心莲内脂对模型小鼠的影响。结果：穿心莲内脂能明显改善感染性休克小鼠的肠道水肿,同时可以降低肺、肾、肝脏器损害程度。结论：穿心莲内脂对LPS建立的小鼠感染性休克具有保护作用。 |
| 英文摘要: |
| Objective: The establishment of animal model of septic shock in mice, to observe the effect of Andrographis fat on early septic shock in mice. Methods: the mice by intraperitoneal injection of lipopolysaccharide (LPS) caused by septic shock model, to observe the effect of Andrographis paniculata in lipid of mice. Results: Andrographis Paniculta lactone can significantly improve infection shock mice intestinal edema, also can reduce lung, kidney, liver damage degree. Conclusion: andrographolide fat establishment of LPS mice with septic shock has protective effect. |
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