| 张冬英,吴耀南.藿朴夏苓汤加减联合四联疗法治疗幽门螺杆菌相关性胃炎脾胃湿热证临床研究[J].实用中西医结合临床,2016,16(7): |
| 藿朴夏苓汤加减联合四联疗法治疗幽门螺杆菌相关性胃炎脾胃湿热证临床研究 |
| Clinical study on the Huopu Xialing decoction combined with quadruple therapy on the treatment of Helicobacter pylori associated gastritis of spleen stomach damp heat syndrome |
| 投稿时间：2016-06-30 修订日期：2016-06-30 |
| DOI： |
| 中文关键词: 藿朴夏苓汤加减 四联疗法 幽门螺杆菌 相关性胃炎 临床效果 |
| 英文关键词: huopuxialing Decoction quadruple therapy Helicobacter pylori gastritis clinical effect |
| 基金项目: |
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| 摘要点击次数: 797 |
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| 中文摘要: |
| 目的：探索藿朴夏苓汤加减联合四联疗法治疗幽门螺杆菌相关性胃炎脾胃湿热证临床效果。方法：对我院2013年5月到2015年10月接收的105例幽门螺杆菌相关性胃炎患者进行治疗,首先征得患者同意后将105例病例按照随机序号分为对照组和观察组；对照组52例,观察组53例,对照组采用常规四联疗法治疗,观察组在对照组基础上联合使用藿朴夏苓汤加减治疗；治疗结束后对两组效果进行观察比较。结果：观察组不良反应发生率为1.9%,低于对照组3.8％,结果不具有显著性差异(P>0.05)。不良反应未经特殊干预后自行消失,未对患者产生较大的影响。但观察组总有效率高于对照组,观察组治疗总有效率为96.2%,明显高于对照组的75.0%,结果有显著性差异(P<0.05)。观察组患者Hp清除率为94.3%,高于对照组的76.9%,两组比较存在明显差异(P<0.05)。结论：藿朴夏苓汤加减联合四联疗法治疗幽门螺杆菌相关性胃炎脾胃湿热证临床效果良好,基本无明显不良反应,且能够明显提高患者的HP根除率,同时提高治疗效果,因而值得临床借鉴使用。 |
| 英文摘要: |
| Objective: To explore the clinical effect of Huopu Xialing decoction combined with quadruple therapy on the treatment of Helicobacter pylori associated gastritis of spleen stomach damp heat syndrome. Methods: 105 cases of Helicobacter pylori associated gastritis were selected from May 2013 to October 2015 in our hospital. These patients were divided into the control group and the observation group. The former were treated by conventional quadruple therapy, the latter plus huopuxialing decoction. Results: the incidence rate of adverse reactions in the observation group was 1.9%, lower than that of the control group(3.8%), and the results were not significant difference (P>0.05). Adverse reactions have disappeared, and have not had a greater impact on patients. But the total effective rate of the observation group was 96.2%, higher than that of the control group (75%), and the results were significant difference (P<0.05). The HP clearance rate of the observation group was 94.3%, higher than that of the control group (76.9%), and there was a significant difference (P<0.05). Conclusion: Huopu Xialing decoction combined with quadruple therapy on treatment of Helicobacter pylori associated gastritis of spleen stomach damp heat syndrome, has better clinical effect. There is no obvious adverse reaction, and can significantly improve the HP eradication rate and efficacy, which is worthy of clinical use. |
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