| 黄志胜.氟比洛芬酯超前镇痛降低小儿股骨骨折术后自控镇痛舒芬太尼用量的作用分析[J].实用中西医结合临床,2015,15(9):10-12 |
| 氟比洛芬酯超前镇痛降低小儿股骨骨折术后自控镇痛舒芬太尼用量的作用分析 |
| Analysis of the Preemptive Analgesia Effect of Flurbiprofen Axetil to Reduce the Dosage of Sufentanil used for Postoperative Analgesia after the Pediatric Femoral Fracture |
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| DOI： |
| 中文关键词: 术后镇痛 氟比洛芬酯 舒芬太尼 |
| 英文关键词: Postoperative analgesia Flurbiprofen axetil Sufentanil |
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| Objective: To analyze the preemptive analgesia effect of flurbiprofen axetil to reduce the dosage of sufentanil used for postoperative analgesia after the pediatric femoral fracture. Method: From October 2013 to August 2014, 78 children of femoral fracture with elastic intramedullary nail fixation in our hospital were randomly divided into control group and experimental group, each group with 39 cases. The control group was given patient-controlled intravenous analgesia of sufentanil after operation, the experimental group was given flurbiprofen axetil when sewing skin and postoperative reduced 50% dosage of sufentanil. After the operation, observed the pain scores, the sedation scores, the numbers of press analgesia pump in 1 h, 4 h, 8 h, 12 h and 24 h and the incidence of adverse drug reactions. Results: After the operation, the pain scores of experimental group in 1 h, 4 h, 8 h, 12 h and 24 h were lower than the control group, but the difference was not statistically significant, P＞0.05; the sedation scores of experimental group were lower than the control group, the difference was statistically significant, P＜0.05; the incidence of adverse reactions in the experimental group was lower than that in the control group, with statistically significant difference, P＜0.05; and the numbers of press analgesia pump in the two groups were similar, with no significant difference, P＞0.05. Conclusion: Preemptive analgesia with flurbiprofen axetil can provide good analgesic effect for children with fracture, at the same time can effectively reduce the dosage of sufentanil and the occurrence of adverse reactions, and with higher safety. |
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