| 王姝彦.肥胖儿童血清C反应蛋白与胰岛素抵抗指数关系的研究王姝彦[J].实用中西医结合临床,2015,15(7): |
| 肥胖儿童血清C反应蛋白与胰岛素抵抗指数关系的研究王姝彦 |
| Study on the relationship between protein and insulin resistance index in obese children serum C-reactive |
| 投稿时间：2015-06-11 修订日期：2015-07-16 |
| DOI： |
| 中文关键词: 肥胖儿童 血清C反应蛋白 代谢综合征 相关性 |
| 英文关键词: Severe acute pancreas Invasive blood pressure monitoring Continuous blood purification |
| 基金项目: |
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| 中文摘要: |
| 目的：分析并探讨肥胖儿童血清C反应蛋白(CRP)与代谢综合征的相关性研究。方法：选取2013年01月-2014年10月期间在我院检查的单纯性肥胖儿童50例为观察组,选取同期体检健康儿童50例为对照组。检测患者血清CRP、血压、总胆固醇、甘油三酯、空腹血糖、胰岛素水平。计算BMI、评估胰岛素抵抗指数,并采用Spearman方法分析CRP与上述各项指标的关系。结果：观察组CRP为(1.82±0.85)mg/L,对照组CRP为(0.78±0.21)mg/L。观察组血清CRP明显高于对照组,经统计学检验,差异有统计学意义(P<0.05)。观察组BMI、收缩压、胰岛素、TC、TG、HOMA-IR等各项指标也显著高于对照组,经统计学检验,差异有统计学意义(P<0.05)。血清CRP水平与BMI (r=0.53,P<0.05)、收缩压 (r=0.21,P<0.05)、胰岛素 (r=0.68,P<0.05)、TG (r=0.29,P<0.05)和HOMA-IR(r=0.20,P<0.05)呈正相关。结论：肥胖儿童血清CRP明显高于正常儿童,且与代谢综合征关系密切,临床上要注意儿童肥胖情况,及时的采取相关对策。 |
| 英文摘要: |
| Objective: To analyze and discuss child obesity serum C-reactive protein (CRP) and the correlation between metabolic syndrome. Methods: January 2013 - in simple obese children in our hospital in October 2014 examined 50 cases during the observation group, choose the same period 50 cases of physical health of children as the control group. Detect serum CRP, blood pressure, total cholesterol, triglycerides, fasting glucose and insulin levels. Calculate BMI, assessment of insulin resistance index, and using Spearman to analyze the relationship between CRP and the indicators above. Results: The observation group CRP (1.82 0.85) mg/L, control group CRP (0.78 0.21) mg/L. The serum levels of CRP were significantly higher than the control group, the statistical test, the difference was statistically significant (P<0.05). The observation group BMI, systolic pressure index, insulin, TC, TG, HOMA-IR are significantly higher than the control group, the statistical test, the difference was statistically significant (P<0.05). The serum level of CRP and BMI (r=0.53, P<0.05), systolic blood pressure (r=0.21, P<0.05), insulin (r=0.68, P<0.05), TG (r=0.29, P<0.05) and HOMA-IR (r=0.20, P<0.05) were positively correlated. Conclusion: The serum CRP in obese children was significantly higher than normal children, and with the metabolic syndrome is closely related to, pay attention to childhood obesity clinical situation, to take timely countermeasures. |
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