| 王哲 路芳.逆流法建立大鼠子宫内膜异位症模型[J].实用中西医结合临床,2015,15(6):3-4,32 |
| 逆流法建立大鼠子宫内膜异位症模型 |
| Establishing Ratendometriosis Model with Reflux Method |
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| DOI： |
| 中文关键词: 子宫内膜异位症 动物模型 逆流法 |
| 英文关键词: Endometriosis Animal models Reflux method |
| 基金项目:山东省中医药科学研究项目（编号：2010-093） |
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| 中文摘要: |
| 目的：通过与种植法建模对比，探讨逆流法建立大鼠子宫内膜异位症模型的可行性及建模成功率。方法：研究分逆流组、种植组、空白组，分别进行手术，术后8周观察组织形态变化并采静脉血检测EMAb、CA125，判定成模情况。结果：逆流组成模率为70%，种植组成模率90%。结论：逆流法建模成功，但成模率较种植法稍低。 |
| 英文摘要: |
| Objective: To discuss the feasibility and success rate of establishing the rat endometriosis model by comparing reflux method with planting method. Method: Lab rats were divided randomly into three groups: reflux group, planting group and control group. Each group were given surgery respectively and tissue morphological variations and EMAb and CA125 in venous blood were observed and tested 8 weeks afterward to compare the conditions of each group. Results: The success rate of reflux model was 70%, and the rate of planting model was 90%. Conclusion: Modeling with reflux method can achieve high success rate but the rate is lower than modeling with planting method. |
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