| 王凯 张晶 杜亚君 李兴艳.血府逐瘀胶囊治疗老年急性心肌梗死患者PCI术后再狭窄的疗效观察[J].实用中西医结合临床,2015,15(2):3-5 |
| 血府逐瘀胶囊治疗老年急性心肌梗死患者PCI术后再狭窄的疗效观察 |
| Effects of Xuefuzhuyu Capsules on the Restenosis of AMI after Percutaneous Coronary Intervention (PCI) in Elderly Patients |
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| DOI： |
| 中文关键词: 急性心肌梗死 老年 PCI术后再狭窄 血府逐瘀胶囊 |
| 英文关键词: Acute myocardial infarction Elderly patients Restenosis after percutaneous coronary intervention Xuefuzhuyu capsules |
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| 中文摘要: |
| 目的：探讨血府逐瘀胶囊对老年急性心肌梗死患者经皮冠状动脉介入术后再狭窄的辅助临床疗效。方法：将经冠状动脉造影明确诊断为冠心病AMI而且经PCI治疗的住院病人，随机分为试验组与对照组各75例。对照组采用常规治疗方法，试验组采用常规治疗+血府逐瘀胶囊治疗。观察两组再狭窄的生化指标内皮素-1、C反应蛋白、一氧化氮的水平及1年中心绞痛发生情况和冠脉造影情况。结果：试验组有效率为88.0%，对照组有效率为74.7%，两组有效率差异有统计学意义（P＜0.05）；试验组冠状动脉造影再狭窄率为10.7%，对照组为23.3%，两组再狭窄率差异有统计学意义（P＜0.05）；两组治疗后ET-1、CRP、NO差异均有统计学意义（P＜0.05）。结论：血府逐瘀胶囊作为植物用药，合并常规治疗方法对于老年急性心肌梗死患者有明显的降低PCI术后再狭窄的作用。 |
| 英文摘要: |
| Objectives: To investigate the effects of Xuefuzhuyu capsules on the restenosis of elderly patients with AMI after PCI. Methods: From Jan 2011 to Dec 2012, 150 elderly patients with AMI after PCI were divided into 2 groups with conventional treatment or conventional treatment plus Xuefuzhuyu capsules. The plasma levels of restenosis markers including endothelin-1, CRP, NO were tested, coronary arteriography was carried out to measure the restenosis situation, angina attack frequencies were also recorded. Results: The effective rate of the experimental group was 88.0%, the control group was 74.7%, the difference between groups was statistically significant (P＜0.05); the restenosis rate was 10.7% by angiography in the experimental group, and the control group was 23.3%, the difference between groups was statistically significant (P＜0.05)；endothelin-1, CRP, NO between two groups were also statistically significant (P＜0.05). Conclusions: Xuefuzhuyu capsules is helpful in prevention restenosis of elderly patients with AMI after PCI. |
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