| 杨晓艳.疏肝解郁胶囊配合氟伏沙明治疗老年期抑郁症研究[J].实用中西医结合临床,2014,14(7):13-14 |
| 疏肝解郁胶囊配合氟伏沙明治疗老年期抑郁症研究 |
| The Study on Senile Depression Treated by Shuganjieyu Capsule Combined with Fluvoxamine |
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| DOI： |
| 中文关键词: 老年期抑郁症 疏肝解郁胶囊 氟伏沙明 |
| 英文关键词: Senile depression Shuganjieyu capsule Fluvoxamine |
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| 摘要点击次数: 698 |
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| 中文摘要: |
| 目的：研究探讨疏肝解郁胶囊配合氟伏沙明治疗老年期抑郁症的临床疗效。方法：选取2012年2月~2013年6月在我院进行检查且确诊为老年期抑郁症的68例患者，随机分为观察组和对照组各34例，观察组予疏肝解郁胶囊联合氟伏沙明治疗；对照组给予氟伏沙明治疗，疗程均为6周。用药后第2、4、6周末对患者进行随访，并用汉密尔顿抑郁量表（HAMD）和不良反应量表（TESS）进行疗效评定。结果：观察组总有效率为88.2%，对照组总有效率为85.3%，两组疗效比较差异无显著性；但观察组不良反应比对照组轻，差异有统计学意义，P＜0.05。结论：疏肝解郁胶囊配合氟伏沙明与单纯应用氟伏沙明治疗老年期抑郁症的临床疗效相当，但疏肝解郁胶囊能提高患者对氟伏沙明的耐受性，减轻不良反应。 |
| 英文摘要: |
| Objective: To explore the clinical effect of Shuganjieyu capsule with fluvoxamine in the treatment of senile depression. Methods: 68 Cases who had been examined and diagnosed with senile depressionpatients, in our hospital from February 2012 to February 2013, the observation group (34 cases) was treated by Shuganjieyu capsule combined with fluvoxamine; the control group (34 cases) was treated by fluvoxamine only, all patients were treated for 6 weeks. The patients were followed up after second, fourth, sixth weekend, and evaluated the efficacy and adverse reaction of drugs by using the Hamilton Depression Rating Scale (HAMD) and adverse drug reaction scale (TESS). Results: The total effective rate of the observation group was 88.2%, the control group was 85.3%, there was no significant between the two groups; but the side effects of the observation group was less than the control group, the difference was statistically significant(P<0.05). Conclusion: The clinical curative effect of Shuganjieyu capsule combined with fluvoxamine is as good as the simple application of fluvoxamine in the treatment of senile depression, but Shuganjieyu capsule can improve the tolerance to fluvoxamine, alleviate the adverse reaction. |
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