| 周凤 邓幼清 陈小红 喻淑琴 曾春 黄小卿 喻荣 陈军 谭彧 吴华东 刘兴媛 杨得奖 李新明.注射用丹参多酚酸治疗脑梗死恢复期（瘀血阻络型）临床研究[J].实用中西医结合临床,2013,(8):8-9，13 |
| 注射用丹参多酚酸治疗脑梗死恢复期（瘀血阻络型）临床研究 |
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| DOI： |
| 中文关键词: 脑梗死 恢复期；瘀血阻络型；注射用丹参多酚酸；疗效；安全性 |
| 英文关键词: Cerebral infarction Recovery stage Blood stasis type Salvianolate injection Therapeutic effect Safety |
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| 中文摘要: |
| 目的：评价注射用丹参多酚酸治疗脑梗死恢复期（瘀血阻络型）的疗效和安全性。方法：选取脑梗死恢复期（瘀血阻络型）患者72例，注射用丹参多酚酸0.13 g溶于0.9%氯化钠250 mL中，静脉滴注，1次/d，治疗14 d后评价治疗的有效性和安全性。结果：治疗后患者神经功能缺损评分、残障指数及日常生活活动能力明显改善(P＜0.01)；治疗期间不良事件发生率为8.3%，主要为体温、血压升高，ALT、AST、GGT及CK异常，均为轻、中度。结论：注射用丹参多酚酸治疗脑梗死恢复期比较安全，能有效改善患者的临床症状。 |
| 英文摘要: |
| Objectives：To further assess the efficacy and safety of Salvianolate injection on recovery stage of cerebral infarction. Methods: 72 Patients on recovery stage of cerebral infarction (blood stasis type) were enrolled and were given 0.13 g Salvianolate injection dissolved in 250 mL 0.9% sodium chloride injection,once a day.Its efficacy and saftey would be evaluated after treatment for 14 days. Results:After treatment,the neurological deficit scores, modified Rankin Scale and Barthel index were improved significantly (P＜0.01);the adverse events happened 8.3% in all the patients,mainly elevated temperature、blood pressure, ALT、AST、GGT and CK abnormalities. Conclusion：Salvianolate injection is safety and efficient on recovery stage of cerebral infarction. |
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