| 范海生 张淑君 梁顺美.丙酸倍氯米松鼻喷雾剂合依匹斯汀治疗变应性鼻炎临床研究[J].实用中西医结合临床,2013,(2):1-2 |
| 丙酸倍氯米松鼻喷雾剂合依匹斯汀治疗变应性鼻炎临床研究 |
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| DOI： |
| 中文关键词: 丙酸倍氯米松鼻喷雾剂 依匹斯汀 变应性鼻炎 治疗 |
| 英文关键词: Beclometasone Dipropionate nasal spray Epinastine Allergic rhinitis Treatment |
| 基金项目:广东省佛山市卫生局科研基金（项目编号：2011294） |
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| 中文摘要: |
| 目的：评价丙酸倍氯米松鼻喷雾剂联合依匹斯汀治疗变应性鼻炎(allergic rhinitis，AR)的临床疗效。方法：159例AR患者采用随机、对照方法，治疗组80例，用丙酸倍氯米松鼻喷雾剂喷鼻，2次/d，每次各鼻孔2揿，依匹斯汀片口服，1次/d，每次10 mg；对照组79例，用丙酸倍氯米松鼻喷雾剂喷鼻，2次/d，每次各鼻孔2揿；疗程均为4周。分析比较治疗前、后各项观察指标。结果：治疗1个疗程后，大部分患者临床表现均有明显改善；治疗组总有效率为92.5% ，对照组为73.4%。两组治疗前后临床表现比较有统计学意义（P <0.05），两组总有效率比较差异有统计学意义(P <0.05)。结论：丙酸倍氯米松鼻喷雾剂联合依匹斯汀应用见效快，效果好，能有效缓解AR患者鼻部症状，值得推广。 |
| 英文摘要: |
| Objective:To evaluate the efficacy of beclometasone dipropionate nasal spray with epinastine treating allergic rhinitis(AR).Methods:159 Cases with AR were randomly divided into two groups,treatment group(80 cases)and control group(79 cases).In the treatment group,patients received beclometasone dipropionate nasal spray twice a day,two sprays in each nostril,and then take epinastine orally once a day with a dosage of 10 mg.In the control group，the patients received beclometasone dipropionate nasal spray twice a day,two sprays in each nostril.The course was 4 weeks.The efficacy of both groups were analyzed.Results:After one course of treatment，the clinical manifestations on most patients were significantly improved,with total effective rates of 92.5% and 73.4% in the treatment group and control group respectively.There was statistic significance on clinical manifestations before and after treatment between the two groups(P <0.05),while significant difference on total effective rates between the two groups(P <0.05).Conclusion:The combimation of beclometasone dipropionate nasal spray with epinastine is quick with good effects for local application,which can effectively relievelocal symptoms for patients with AR. |
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